Sciatic Nerve Block, Adductor Canal Block, or IPACK Block

Post Operative Pain Clinical Trial

Official title:

Femoral Nerve Block Combined With Sciatic Nerve Block Adductor Canal Block Or (Interspace Between The Popliteal Artery And The Capsule Of The Posterior Knee) IPACK Block For Postoperative Analgesia After Major Knee Surgeries

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05684107
• Other study ID #: 10/2022ANETH2
• Status: Recruiting
• Phase: N/A
• Start date: November 1, 2022
• Est. completion date: December 1, 2023

Study information

• Verified date: January 2023
• Source: Menoufia University
• Contact: mostafa saieed saieed mansour, MD
• Phone: 01225484055
• Email: mostafa.said[@]med.menofia.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Comparison between local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK) versus adductor canal block (ACB) or sciatic nerve block (anterior approach) in combination with femoral nerve block for postoperative analgesia in major knee surgeries.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: December 1, 2023
• Est. primary completion date: November 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 75 Years

Eligibility

Inclusion Criteria:

• ASA I or II physical status
• undergoing elective major knee surgery

Exclusion Criteria:

• refusal of the patients to give informed consent,
• preexisting coagulation disorders,
• known allergies to aminoamide local anesthetics,
• local infection at the site of the block,
• morbid obesity,
• hepatic and renal diseases
• patients with psychological disorders

Related Conditions & MeSH terms

• Pain, Postoperative
• Post Operative Pain

Intervention

Procedure:
• IPACK block
the probe is applied to the popliteal fossa for identification of the popliteal artery and femur. Then, the probe is slid distally for revealing the two femoral condyles followed by proximal sliding of the probe until the humps of the femoral condyles disappeared and the flat metaphysis appeared. a spinal needle 22G x 3.5 inches is advanced from the lateral aspect and directed across the space between the popliteal artery and femur and once the needle reached the medial edge of the femur, nearly at the level of the popliteal artery, negative aspiration is confirmed and 20 ml of bupivacaine 0.25% is injected incrementally as the needle was withdrawn
• adductor canal block
the transducer is placed anteromedially, approximately at the junction between the middle and distal third of the thigh or somewhat lower. The saphenous nerve block should be performed at the most distal level where the artery still lies immediately deep to the sartorius muscle, thus minimizing the amount of motor nerve block of the vastus medialis; an adductor canal nerve block is typically performed more proximally, around the mid-thigh level. The needle is inserted in-plane in a lateral-to-medial orientation and advanced toward the femoral artery. Once the needle tip is visualized anterior to the artery and after careful aspiration, 20 ml of bupivacaine 0.25% is injected incrementally as the needle was withdrawn
• sciatic nerve block
patient in a supine position with the hip and knee on the operated side flexed and the leg externally rotated at approximately 45 degrees. The ultrasound transducer is first positioned perpendicular to the skin approximately 8 cm distal to the inguinal crease. The location is then scanned by sliding and tilting the transducer until a clear transverse image of the hyperechoic sciatic nerve located posterior and medial to the lesser trochanter is obtained. a spinal needle 22G x 3.5 inches is advanced parallel and in line with the ultrasound transducer while the sciatic nerve is kept in the middle of the screen. The needle is advanced slowly under real-time ultrasound guidance until it is near the nerve then negative aspiration is confirmed and 20 ml of bupivacaine 0.25% is injected incrementally as the needle was withdrawn

Locations

Country	Name	City	State
Egypt	Faculty of Medicine, University Hospitals	Shibin Al Kawm	Menoufia

Sponsors (1)

Lead Sponsor	Collaborator
Menoufia University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change of visual analogue scale	a scale from 0 to 10 as the patient will be asked to express his pain on the scale higher scale means a worse outcome	change from 0 level every 1 hour for 1st 6 hours,then every 4 hours for next 24 hours and on movement
Secondary	time for fisrt analgesic request	when VAS is 4 or more longer time means a better outcome	up to 48 hours
Secondary	total morphine consumption	intraoperative and post operative higher consumption means a worse outcome	up to 48 hours