Analgesia After Video-Assisted Thoracic Surgery

Post Operative Pain Clinical Trial

Official title:

Analgesic Efficacy of Ultrasound-Guided Deep Serratus Anterior Plane Block, Local Wound Infiltration, and Thoracic Paravertebral Block After Uniportal Video-Assisted Thoracic Surgery: A Randomized Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05094323
• Other study ID #: 10 2021
• Status: Recruiting
• Phase: Phase 2
• Start date: February 18, 2022
• Est. completion date: January 2023

Study information

• Verified date: February 2022
• Source: Assiut University
• Contact: Seham M Moeen, MD
• Phone: 01006386324
• Email: seham.moeen[@]aun.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS).

Description:

Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS). Adequate postoperative pain relief is imperative to hasten functional recovery, accelerate discharge from the hospital, and reduce chronic postsurgical pain.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 102
• Est. completion date: January 2023
• Est. primary completion date: January 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Patients scheduled for uniportal VATS under general anesthesia, ASA status I-III, aged from 18 to 70 years old of both sex.

Exclusion Criteria:

• Contraindications to regional block
• Pregnancy
• Body mass index (BMI) > 30 Kg/m2
• Psychiatric diseases
• Severe renal, liver, or cardiac dysfunction

Related Conditions & MeSH terms

• Pain, Postoperative
• Post Operative Pain

Intervention

Drug:
• Ultrasound-guided deep serratus anterior plane block with isobaric bupivacaine
Patients will receive ultrasound-guided deep serratus anterior plane block with isobaric bupivacaine.
• Local wound infiltration with isobaric bupivacaine
Patients will receive local wound infiltration with isobaric bupivacaine.
• Ultrasound-guided thoracic paravertebral block with isobaric bupivacaine
Patients will receive ultrasound-guided thoracic paravertebral block with isobaric bupivacaine.

Locations

Country	Name	City	State
Egypt	Seham M. Moeen	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time to first analgesic requirement	Assessed in minutes	24 hours after surgery
Secondary	Postoperative pain intensity	Assessed by the numerical rating pain scale, an 11-point scale graded from 0 to 10 (0 = no pain, 10 = the worst imaginable pain)	24 hours after surgery