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Post-operative Pain clinical trials

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NCT ID: NCT05475795 Recruiting - Post Operative Pain Clinical Trials

Postoperative Pain After Pulpectomy of Primary Molars Using Different Obturation Materials

Start date: June 9, 2022
Phase: N/A
Study type: Interventional

Testing postopertive pain after pulpectomy of primary molars with Metapex and Endoflas using modified Wong-Baker scale of pain.

NCT ID: NCT05441150 Recruiting - Post Operative Pain Clinical Trials

Intravenous Ketamine Infusion on Postoperative Analgesia of Living Liver Donors

Start date: June 1, 2022
Phase: Phase 4
Study type: Interventional

Because of the insufficiency of cadaveric organs and increasing need for organs, the interest in living donor liver transplantation have been greatly increased. The relative reduction of the remaining liver after the operation in Living Liver Donors makes it difficult and compelling to choose a very effective and very safe method in the management of postoperative analgesia. Opioids are the main agents used in the postoperative analgesia of Live Liver Donors. Opioids have serious side effects such as respiratory depression, apnea, circulatory collapse, coma, and death. Both short-term and long-term administration of opioids cause acute opioid-induced hyperalgesia. Ketamine, an NMDA receptor antagonist, has been hypothesized to counter opioid tolerance and NMDA receptor-mediated central sensitization. Various studies and systematic reviews have shown that low-dose ketamine has an opioid-sparing effect in all surgical patients. Although low-dose ketamine has been shown to be beneficial overall in relieving pain, it is unclear whether it has an identified benefit in hepatectomy cases. The aim of this clinical trial was to evaluate the effect of low-dose ketamine administration on postoperative analgesia in living donor liver donors undergoing right hepatectomy procedure.

NCT ID: NCT05439837 Recruiting - Post Operative Pain Clinical Trials

Paracoracoid Subscapularis Plane Block Versus Iso Block for Shoulder Surgery for Shoulder Surgery

Start date: June 14, 2022
Phase: N/A
Study type: Interventional

Shoulder surgery is the second orthopedic operation cause post operative pain Interscalene block is the standard block for shoulder surgery but it cause phrenic nerve block and diaphragmatic hemipareses Iso block is the block used to block the brachial plexuses cord and suprascapular nerve And paracoracoid subscapularis block supra scapular nerve in supra scapular fosa and axillary nerve as it curves around humeral head

NCT ID: NCT05405127 Recruiting - Low Back Pain Clinical Trials

Breathing and Core Stability Exercise Effects on Lumbopelvic Pain

Start date: May 30, 2022
Phase: N/A
Study type: Interventional

Lumbopelvic pain refers to self-reported pain in areas of lower region, anterior and posterior pelvic tilt or combination of these. Physical therapy interventions used are breathing exercises with and without core stability exercises. Tool used were Pain Pressure Algometer and Oswestry Disability Index.

NCT ID: NCT05370924 Recruiting - Chronic Pain Clinical Trials

Assessment of the Development of Postoperative Persistent Postoperative Pain

Start date: February 20, 2021
Phase:
Study type: Observational

During the postoperative period, it is possible to observe the development of acute pain, which lasts no longer than a week after surgery. However, sometimes some patients see the prolongation of this pain beyond the healing time of the tissue, turning into a chronic condition. Persistent postoperative pain is a disease with a complex and still unknown etiology, affecting between 5 and 75% of the population. The development of persistent postoperative pain is a rather important issue since the physician managing the patient must on the one hand ensure adequate analgesia, and on the other hand, minimize the risk of continued opioid use in the case of chronicization. In a study conducted analyzing the prevalence of persistent postoperative pain in various surgeries it was seen to occur more frequently in limb amputation (prevalence >85%), thoracotomy (prevalence 48%), knee arthroplasty (prevalence 44%), laminectomies, and spinal arthrodesis (prevalence 5-46%), and hip replacement (prevalence 27%) making this type of pain more frequent in the patient undergoing orthopedic surgery. As the mechanisms behind its development have not yet been fully clarified, efforts to study the clinical factors associated with the onset of this pathology have been attempted. As there is no way in the literature to stratify the risk of the population in order to prevent the development of postoperative pain, based on the variables reported by different studies, it was decided to administer in patients referred to the Orthopedics and Traumatology 1 U and Orthopedics and Traumatology 3 U department at the Orthopedic Trauma Center of Turin questionnaires to assess the development of chronic pain for screening purposes and to contribute to the improvement of the long-term management of these patients in the postoperative period.

NCT ID: NCT05360433 Recruiting - Post Operative Pain Clinical Trials

Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management

Start date: November 1, 2020
Phase: Phase 4
Study type: Interventional

This is a randomized controlled trial involving 170 opioid naive women ages 19-40 undergoing scheduled C-sections at Carilion Roanoke Memorial Hospital. Participants are randomized to receive either 10 or 20 tabs of oxycodone 5mg as an initial postoperative prescription in a double-blinded parallel trial design. Outcome metrics related to overall opioid consumption and patient satisfaction with pain management are collected at three different time points post-operative: 2-3 days (in hospital), 10-14 days, and 6 weeks.

NCT ID: NCT05356663 Recruiting - Post Operative Pain Clinical Trials

Comparative Effects of Hold Relax Technique and Mulligan Mobilization in Post Operative Knee Joint

Start date: April 15, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the comparative effects of hold relax technique and mulligan mobilization on pain, ROM and function in post operative knee joint.

NCT ID: NCT05338671 Recruiting - Post Operative Pain Clinical Trials

Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment

Start date: September 29, 2021
Phase: Phase 4
Study type: Interventional

This study will assess the efficacy of two local anesthetics (2% lidocaine 1:100,000 epinephrine and 0.5% bupivicaine 1:200,000 epinephrine) in reducing post-operative pain in patients receiving endodontic treatment.

NCT ID: NCT05338320 Recruiting - Post Operative Pain Clinical Trials

Postoperative Analgesia in Patients Undergoing Elective Lumbar Fusion Operations Under General Anesthesia

Start date: May 10, 2022
Phase: Phase 4
Study type: Interventional

It was proven that intrathecal opioids are considered as an effective means of pain control in several major surgical interventions including spine surgeries. Intrathecal morphine added to a spinal anesthesia reduces acute pain after spine surgeries but has side effects, including dose dependent respiratory depression, nausea, vomiting, pruritus, and sedation. Ultrasound guided Erector Spinae Plane Block (ESPB) was first described in 2016.Recent case reports suggest a positive effect of ultrasound guided ESPB on pain for multiple indications including lumbar spine fusion and scoliosis surgery, with a very low risk of complications as there are no structures in close proximity at risk of needle injury.

NCT ID: NCT05278494 Recruiting - Post-operative Pain Clinical Trials

Dextromethorphan for Treatment of Postoperative Pain

Start date: September 15, 2022
Phase: N/A
Study type: Interventional

A Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Perioperative Dextromethorphan compared to Placebo for the Treatment of Postoperative Pain