Post-Dural Puncture Headache Clinical Trial
Official title:
Sphenopalatine Ganglion Block With Adrenaline Additive for Post-Dural Puncture Headache in Orthopedic Patients: A Randomized Controlled Study
Verified date | December 2020 |
Source | Tanta University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The aim of this study is to assess the efficacy, onset and duration of analgesia of sphenopalatine ganglion bock (SPGB) using lidocaine 4% with adrenaline as a treatment of postoperative Post dural puncture headache (PDPH) of orthopedic patients after lower limbs surgeries.
Status | Not yet recruiting |
Enrollment | 60 |
Est. completion date | May 20, 2021 |
Est. primary completion date | May 10, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Admitted to the orthopedic department - Complaining of criteria of severe post-dural puncture headache within 7 days following subarachnoid block used for lower limbs surgeries. - American Society of Anesthesiologists (ASA) physical status I and II. Exclusion Criteria: - Patient refusal or uncooperative. - Patients with uncontrollable hypertension. - Patient with known coagulopathy. - Patient with nasal septal deviation, polyp, history of nasal bleeding. - Patient with allergy to local anesthetics - American Society of Anesthesiologists physical status>2. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Tanta University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Efficacy of analgesia demonstrated by visual analogue scale (VAS) less than 4 (effective) in the first 48 hours | Efficacy of analgesia demonstrated by visual analogue scale (VAS) less than 4 (effective) in the first 48 hours.
VAS ranges from 0 to 10; 10 with worse outcome |
48 hours | |
Secondary | Onset of analgesia | The onset time till VAS= 4 | 48 hours | |
Secondary | Duration of analgesia | Duration with VAS< 4 | 48 hours | |
Secondary | Adverse events | Local anesthetic toxicity, hypertension, postoperative epistaxis, cheek hematoma and hypoesthesia of the palate | 48 hours |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04091321 -
Association Between Chronic Headache and Back Pain With Childbirth
|
||
Recruiting |
NCT05202574 -
Comparing the Effects of Ondansetron Versus Dexamethasone on the Incidence of Post-dural Puncture Headache (PDPH) , Nausea and Vomiting After Spinal Anaesthesia of Parturients Undergoing Caesarean Section
|
Phase 2 | |
Terminated |
NCT02813655 -
Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE)
|
Phase 2 | |
Completed |
NCT02522013 -
Aminophylline for Patients With Post-Dural Puncture Headache
|
Phase 3 | |
Recruiting |
NCT06444737 -
Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia
|
N/A | |
Completed |
NCT05301387 -
The Effect of Ganglion Sphenopalatine Block (GSP-block) Follow-Up
|
||
Recruiting |
NCT05637645 -
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
|
N/A | |
Recruiting |
NCT05116930 -
Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture
|
Phase 2 | |
Terminated |
NCT03430531 -
Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
|
Phase 2 | |
Completed |
NCT04401878 -
SGB in Management of Patients With PDPH Using TCD
|
N/A | |
Completed |
NCT04327726 -
Effectiveness of Nebulized Dexmedetomidine for Treatment of Obstetric Post-Dural Puncture Headache
|
N/A | |
Completed |
NCT03475784 -
Two Fluid Strategies for Prevention of Post-dural Puncture Headache
|
Phase 3 | |
Not yet recruiting |
NCT06272916 -
Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.
|
||
Terminated |
NCT02827058 -
The Influence of Needle Diameter on Post Dural Puncture Headache
|
N/A | |
Completed |
NCT05262933 -
Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
|
||
Completed |
NCT04793490 -
Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients
|
N/A | |
Recruiting |
NCT05888324 -
Factors Associated With the Onset of Chronic Headaches in Patients Who Received a Blood Patch in Post Partum
|
||
Completed |
NCT00370604 -
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
|
N/A | |
Completed |
NCT04844229 -
Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache
|
N/A | |
Withdrawn |
NCT03560349 -
RCT of SPG Blocks for Post-dural Headache
|
Phase 2 |