Clinical Trials Logo
  1. Home
  2. Post-Dural Puncture Headache
  3. NCT00370604

Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study

Post-Dural Puncture Headache Clinical Trial

Official title:
Randomized Controlled Trial Examining the Effect of Small Versus Large Tuohy-type Epidural Needles on the Incidence and Severity of Postdural Puncture Headache

Clinical Trial Summary

The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).

Clinical Trial Description

A headache is the most significant complication of dural puncture during epidural placement. This complication leads to longer hospital stays and many repeated visits to hospital for management. Women suffering from severe postdural puncture headache (PDPH) are often bedridden and unable to care for themselves or their babies.The efficacy of epidural blood patch as a "gold standard" therapy is over-estimated by the earlier, poor quality studies. The prevalence of dural puncture during epidural anesthesia using current techniques ranges from 0.03 to 6% in the literature. Of these patients, 70 to 80% will suffer from moderate to severe PDPH. Avoidance of dural puncture is always the goal. However, complete avoidance is unlikely using current techniques of needle placement. This study proposes another method of prevention (i.e., reducing the gauge of the epidural needles if it is shown to be suitable for continuous infusion in adults). Most of the risk factors for developing PDPH cannot be changed (e.g., younger age, female sex, low body mass index, history of migraines). However, epidural needle gauge is a modifiable risk factor. Evidence suggests that the use of smaller gauge epidural needles, like spinal needles, have the potential to reduce the incidence and severity of PDPH. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00370604
Study type Interventional
Source Sunnybrook Health Sciences Centre
Contact
Status Completed
Phase N/A
Start date June 2007
Completion date December 2009
View Details
See also
  Status Clinical Trial Phase
Completed NCT04091321 - Association Between Chronic Headache and Back Pain With Childbirth
Recruiting NCT05202574 - Comparing the Effects of Ondansetron Versus Dexamethasone on the Incidence of Post-dural Puncture Headache (PDPH) , Nausea and Vomiting After Spinal Anaesthesia of Parturients Undergoing Caesarean Section Phase 2
Terminated NCT02813655 - Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE) Phase 2
Completed NCT02522013 - Aminophylline for Patients With Post-Dural Puncture Headache Phase 3
Completed NCT05301387 - The Effect of Ganglion Sphenopalatine Block (GSP-block) Follow-Up
Recruiting NCT05637645 - Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section N/A
Recruiting NCT05116930 - Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture Phase 2
Terminated NCT03430531 - Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache Phase 2
Completed NCT04401878 - SGB in Management of Patients With PDPH Using TCD N/A
Completed NCT04327726 - Effectiveness of Nebulized Dexmedetomidine for Treatment of Obstetric Post-Dural Puncture Headache N/A
Completed NCT03475784 - Two Fluid Strategies for Prevention of Post-dural Puncture Headache Phase 3
Not yet recruiting NCT06272916 - Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.
Terminated NCT02827058 - The Influence of Needle Diameter on Post Dural Puncture Headache N/A
Not yet recruiting NCT05262933 - Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
Completed NCT04793490 - Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients N/A
Recruiting NCT05888324 - Factors Associated With the Onset of Chronic Headaches in Patients Who Received a Blood Patch in Post Partum
Completed NCT04844229 - Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache N/A
Withdrawn NCT03560349 - RCT of SPG Blocks for Post-dural Headache Phase 2
Recruiting NCT06253754 - Pathophysiological Mechanisms and Implication of Treatment in Postural Puncture Headache
Not yet recruiting NCT03385772 - The Sphenopalatine Ganglion Block for Post-dural Puncture Headache N/A