Post Dural Puncture Headache Clinical Trial
Official title:
Systematic Review: Post Dural Puncture Headache After Accidental Dural Puncture: Does Insertion of Spinal Catheter Decrease Incidence of Headaches?
Epidural anesthesia is associated with potential risks and complications, post dural puncture headache (PDPH) one of the most recognized with epidural or spinal anesthesia. Accidental dural punctures occur with approximately 1.5% of all epidural attempts. Studies have suggested that the use of an intrathecal catheter reduces the incidence of PDPH. A systematic review of the existing literature will identify if there is reliable evidence to support this theory. A secondary outcome, headache severity, will also be explored via incidence rates of epidural blood patch, as this intervention is performed as a treatment for the most severe headaches.
Post dural puncture headache (PDPH) is one of the recognized complications experienced with
epidural or spinal anesthesia, resulting from needle puncture of the dura layer of the
meninges. This puncture can be deliberate (during spinal anesthesia) or accidental (during
epidural anesthesia). Dural punctures allow a leak of cerebrospinal fluid, leading to the
characteristic syndrome of PDPH; also known as a spinal headache or low-pressure headache.
Accidental dural punctures occur with approximately 1.5% of all epidural attempts. Studies
have estimated that, within the obstetrical population, headaches resulting from an
inadvertent dural puncture are as high as 50% to 75%.
As the risk of accidental dural punctures (ADP) cannot be eliminated, research has focused
on possible interventions that may be taken in order to avoid the onset of a PDPH, eliminate
its severity, or treat effects. One of the most common and effective treatments being an
epidural blood patch (EBP). More recently, threading the epidural catheter directly into the
intrathecal space after the dural puncture has been recognized as a viable option.
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Time Perspective: Retrospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00809627 -
Caffeine Versus Placebo for Spinal Headaches
|
N/A | |
| Not yet recruiting |
NCT01503788 -
Bedside Sedation for the Prevention of Post Dural Puncture Headache
|
Phase 2 |