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Polyps clinical trials

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NCT ID: NCT05477836 Completed - Colorectal Cancer Clinical Trials

Feasibility and Safety of MiWEndo-assisted Colonoscopy

MiWEndo1
Start date: October 18, 2022
Phase: N/A
Study type: Interventional

The study involves the planned use of a new microwave-based device during colonoscopy procedures in a small group of patients to assess the preliminary safety of its use and lack of normal clinical practice modification. The device is a final design version, which has been previously tested in several preclinical studies, including: phantom studies, an ex vivo study with human tissues, and an in vivo study with animal model (pig).

NCT ID: NCT05474924 Recruiting - CRS Clinical Trials

The Role of Budesonide Intrapolyp Injection in CRSwNP

Start date: August 1, 2022
Phase: Phase 4
Study type: Interventional

Chronic rhinosinusitis with nasal polyps is a common nasal comorbidity with a wide range of symptoms that might cause severe distress and disabilities for patients. Many patients undergo repeated courses of systemic steroids and are exposed to various adverse effects. many cases finally revert to surgery. Budesonide was safely used as a nasal wash in cases of nasal polyps, our aim to determine If intrapolyp injection is a better method for delivering budesonide.

NCT ID: NCT05466903 Recruiting - Colonic Polyp Clinical Trials

Prospective, Randomized, Parallel Clinical Controlled Study of Early Diet Opening on Postoperative Gastrointestinal Hemorrhage in Patients With Colonic Polyps

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Currently, hemorrhage remains the most common postoperative complication in patients with colon polyps, with an incidence of approximately 1.5%. The main reasons for postoperative hemorrhage are: the patient's own condition, the nature of the polyp and the operation. The number of patients treated for colon polyps has increased, postoperative care is confusing, medical resources are wasted, and the time span for postoperative diet recovery is large. However, studies on the effect of postoperative dietary recovery timing on postoperative polyp bleeding are rare.

NCT ID: NCT05405530 Recruiting - Gastric Cancer Clinical Trials

Nasal Mask Kit in Gastrointestinal Endoscopy

NASO
Start date: September 1, 2022
Phase: N/A
Study type: Interventional

Hypoxia is the most common adverse event in gastrointestinal endoscopes sedated with propofol. The nasal mask oxygen kit has good sealing to ensure an adequate oxygen supply and is convenient and economical.The aim of this randomized study was to determine whether the nasal mask oxygen kit reduces the incidence of hypoxia in gastrointestinal endoscopes procedures.

NCT ID: NCT05405478 Not yet recruiting - Nasal Polyps Clinical Trials

Omalizumab Efficacy in Patients With Refractory Nasal Polyps

Start date: June 1, 2022
Phase: Phase 4
Study type: Interventional

in patients with chronic rhinosinusitis with nasal polyps and concomitant asthma, they have a poor therapeutic response and a higher recurrence rate, and treatment in these patients often fails. investigators conducted this study to survey the efficacy of Omalizumab (anti IgE) on patients with refractory nasal polyp to confirm its efficacy entering to treatment guidelines.SNOT-22 score will measure at screening; on day 1; and at weeks 4, 8, 16, and 24 (point range, 0-110, with lower scores indicating better disease control and quality of life .

NCT ID: NCT05349110 Recruiting - Clinical trials for Colorectal Neoplasms

Real-time Diagnosis of Diminutive Colorectal Polyps Using AI

COMET-OPTICAL
Start date: August 20, 2021
Phase:
Study type: Observational

Correct endoscopic prediction of the histopathology and differentiation between benign, pre-malignant, and malignant colorectal polyps (optical diagnosis) remains difficult. Artificial intelligence has great potential in image analysis in gastrointestinal endoscopy. Aim of this study is to investigate the real-time diagnostic performance of AI4CRP for the classification of diminutive colorectal polyps, and to compare it with the real-time diagnostic performance of commercially available CADx systems.

NCT ID: NCT05324137 Active, not recruiting - Clinical trials for Chronic Rhinosinusitis With Nasal Polyps

A Study of CM326 in Patients With Chronic Rhinosinusitis With Nasal Polyps

DUBHE
Start date: July 11, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This is a multi-center, randomized, double blind, placebo-controlled, dose escalation study to evaluate the safety, tolerability, PK, PD, immunogenicity and preliminary efficacy of CM326 in patients with chronic rhinosinusitis with nasal polyps.

NCT ID: NCT05322993 Recruiting - Colonic Polyp Clinical Trials

Improving Polyp Detection Rate by Artificial Intelligence in Colonoscopy

Start date: November 19, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to investigate if the use of artificial intelligence (AI) in colonoscopy improves the polyp detection rate, and if the use of AI has a learning effect.

NCT ID: NCT05309174 Recruiting - Vocal Cord Polyp Clinical Trials

The Study of Bilateral Upper Laryngeal Nerve Block for Supporting the Removal of Vocal Cord Polyps Under Laryngoscopy

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

With the continuous development of microsurgery, supporting laryngoscopy acoustic polyp removal has become a very mature clinical operation. The operation has small trauma, short operation time, fast turnover and needing to wake up as soon as possible, but the supporting laryngoscopy has great stimulation to the throat and great hemodynamic fluctuations. This study aims to evaluate the efficacy of ultrasound guided superior laryngeal nerve block as an adjuvant to general anesthesia during vocal cord polypectomy by laryngoscopy.

NCT ID: NCT05281523 Active, not recruiting - Nasal Polyps Clinical Trials

Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps (ANCHOR-2)

ANCHOR-2
Start date: April 18, 2022
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of depemokimab (GSK3511294) in participants with CRSwNP.