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Polyp of Colon clinical trials

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NCT ID: NCT04551014 Completed - Colo-rectal Cancer Clinical Trials

Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm

Start date: September 16, 2020
Phase: N/A
Study type: Interventional

The focus of the study is to evaluate impact of submucosal injection of EverLift in achieving complete resection during polypectomy of polyps 4-9mm during colonoscopy.

NCT ID: NCT04551001 Completed - Colo-rectal Cancer Clinical Trials

Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy

Start date: September 16, 2020
Phase: N/A
Study type: Interventional

The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.

NCT ID: NCT04500392 Recruiting - Gastric Cancer Clinical Trials

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity

Start date: May 6, 2021
Phase: N/A
Study type: Interventional

Hypoxia is the most common adverse event during gastrointestinal endoscopes sedated with propofol and sufentanil, especially in obese people. In the present study, high-flow nasal cannula oxygenation will be utilized in order to reduce the incidence of hypoxia among obesity.

NCT ID: NCT04442607 Completed - Polyp of Colon Clinical Trials

Clinical vAliDation of ARTificial Intelligence in POlyp Detection

CAD-ARTIPOD
Start date: October 13, 2020
Phase: N/A
Study type: Interventional

This study is an open label, unblinded, non-randomized interventional study, comparing the investigational artificial intelligence tool with the current "gold standard": Data acquisition will be obtained during one scheduled colonoscopic procedure by a trained endoscopist. During insertion, no action will be taken, colonoscopy is performed following the standard of care. Once withdrawal is started, a second observer (not a trained endoscopist but person trained in polyp recognition) will start the bedside Artificial intelligence (AI) tool, connected to the endoscope's tower, for detection. This second observer is trained in assessing endoscopic images to define the AI tool's outcome. Due to the second observer watching the separate AI screen, the endoscopist is blinded of the AI outcome. When a detection is made by the AI system that is not recognized by the endoscopist, the endoscopist will be asked to relocate that same detection and to reassess the lesion and the possible need of therapeutic action. All detections are separately counted and categorized by the second observer. All polyp detections will be removed following standard of care for histological assessment. The entire colonoscopic procedure is recorded via a separate linked video-recorder.

NCT ID: NCT04378660 Completed - Polyp of Colon Clinical Trials

Artificial Intelligence (AI) Validation Study for Polyp Detection

Start date: October 30, 2019
Phase: N/A
Study type: Interventional

Interventional prospective multicenter study: Polyp detection by an automated endoscopic tool as second observer during routine diagnostic colonoscopy

NCT ID: NCT04359355 Recruiting - Adenoma Colon Clinical Trials

Computer-aided Detection of Colorectal Polyps

Start date: January 1, 2020
Phase:
Study type: Observational

In this observational pilot study, we assess the diagnostic performance of an artificial intelligence sytem for automated detection of colorectal polyps.

NCT ID: NCT04357158 Completed - Colorectal Cancer Clinical Trials

Breath Analysis as an Additional Test for Colorectal Cancer Screening to Reduce the Number of Unnecessary Colonoscopies

SCREENER
Start date: May 25, 2020
Phase: N/A
Study type: Interventional

In the past decade, the demand for colonoscopy procedures has increased significantly since the introduction of population-based colorectal cancer (CRC) screening in many western countries. Post-polypectomy surveillance will increase the number of colonoscopy procedures conducted each year even further. The invasive nature of colonoscopy and the associated health-care costs warrant the development of a new non-invasive test to reduce the number of unnecessary colonoscopies. These days, many countries use a non-invasive fecal test for CRC screening which is easy to perform at home, but test characteristics such as sensitivity and specificity are suboptimal. Multiple studies have already shown that volatile organic compound (VOC) analysis has a high diagnostic accuracy for CRC and Advanced Adenomas. An additional VOC analysis, for example through breath testing, in patients with a positive fecal immunochemical test (FIT) may reduce the number of unnecessary colonoscopies. The aim of this study is to validate the diagnostic accuracy of the AeonoseTM to distinguish patients with CRC from healthy controls, and to assess reproducibility of test results.

NCT ID: NCT04203667 Completed - Polyp of Colon Clinical Trials

EndoRotor® Endoscopic Mucosal Resection System for the Colon

Start date: April 18, 2018
Phase: N/A
Study type: Interventional

The EndoRotor® is intended for use (USA labeling) in endoscopic procedures by a trained gastroenterologist to resect and remove tissue, not intended for biopsy, of the gastrointestinal (GI) system including post-endoscopic mucosal resection (EMR) tissue persistence with a scarred base and residual tissue from the peripheral margins following EMR. In this trial investigators will conduct a post-market, prospective, non-randomized, multi-center study for the treatment of subjects with the need for resection of recurrent flat or sessile colorectal lesions where EndoRotor is the primary resection modality of persistent adenoma with a scarred base.

NCT ID: NCT04195646 Completed - Colo-rectal Cancer Clinical Trials

Computer Aided Detection of Polyps During Colonoscopy Procedures

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The focus of the study is to evaluate impact on Adenomas Per Colonoscopy (APC) with a Computer Aided Detection (CAD) software assisting the gastroenterologist during a colonoscopy procedure.

NCT ID: NCT04117100 Recruiting - Colo-rectal Cancer Clinical Trials

Advanced Endo-therapeutic Procedure : Registry-based Observational Study

AE-Registry
Start date: June 1, 2018
Phase:
Study type: Observational [Patient Registry]

Advanced therapeutic endoscopy procedures are of increasing importance to provide minimal invasive treatment for GI diseases. The Centre Hospitalier de l'Université de Montréal as tertiary university center is dedicated to increase the availability of therapeutic endoscopy procedures for our population in Montreal and Quebec.