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NCT01382576 Clinical Trial

Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity

Polycystic Ovary Syndrome Clinical Trial

Official title:
Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity: A Pathophysiological Link Between Inflammation and Impaired Insulin Sensitivity?

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01382576
Other study ID # 1491-81-11/1539-1563
Secondary ID Chitotriosidase
Status Completed
Phase N/A
First received June 10, 2011
Last updated March 9, 2012
Start date January 2010
Est. completion date December 2010

Study information
Verified date December 2010
Source Gulhane School of Medicine
Contact n/a
Is FDA regulated No
Health authority Turkey: Ministry of Health
Study type Observational

Clinical Trial Summary

In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).

Description:

ChT activity is increased in patients with PCOS in concordance with insulin resistance. These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic diseases in this particular patient group.

Recruitment information / eligibility
Status Completed
Enrollment 78
Est. completion date December 2010
Est. primary completion date December 2010
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 18 Years to 35 Years
Eligibility Inclusion Criteria:

- Absence of significant abnormalities on physical examination except hirsutism

- no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy

- normal thyroid function and prolactin level

- absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease

Exclusion Criteria:

- Pregnant

- ovarian tumors

- congenital adrenal hyperplasia or BMI greater than 30 kg/m2

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
Turkey Gulhane School of Medicine Etlik Ankara

Sponsors (1)
Lead Sponsor Collaborator
Gulhane School of Medicine

Country where clinical trial is conducted

Turkey, 

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