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Polycystic Ovary Syndrome clinical trials

View clinical trials related to Polycystic Ovary Syndrome.

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NCT ID: NCT05348967 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Combination of D-chiro-inositol With Ketogenic Diet

Start date: October 14, 2022
Phase: N/A
Study type: Interventional

The study aims to evaluate whether the combination of a product based on D-chiro-inositol and the ketogenic diet can improve the metabolic/endocrine picture of overweight/obese women with PCOS, with insulin resistance, in a shorter time than the ketogenic diet alone

NCT ID: NCT05348265 Completed - Clinical trials for Polycystic Ovary Syndrome

High Intensity Interval Training in PCOS

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Study objective is to determine the effect of High intensity interval training on psychological wellbeing, Anthropometrics and Quality of life in females with Polycystic Ovarian Syndrome

NCT ID: NCT05344547 Completed - Cardiac Disease Clinical Trials

Women With Polycystic Ovary Syndrome Are at High Risk for Cardiac Insults

Start date: March 21, 2020
Phase:
Study type: Observational

Objectives: Evaluation of the cardiovascular (CV) risk in a sample of CV asymptomatic infertile women with polycystic ovary syndrome (PCOS). Patients & Methods: 100 infertile PCOS women older than 30 years (PCOS group) and 50 fertile non-PCOS women (Non-PCOS group) underwent gynecological and laboratory diagnosis and then underwent a diagnostic protocol consisting of determination of body mass index (BMI), Homeostasis model assessment of insulin resistance (HOMA-IR) scoring and cardiologic evaluation using echocardiography, estimation of carotid artery intima-media thickness (CIMT), coronary artery calcium (CAC) score using multi-slice non-contrast cardiac CT and cardiac risk ratio (CRR). Study outcomes included the incidence of abnormal cardiac risk parameters and the determination of the best minimally invasive modality to be used as a screening test for these women.

NCT ID: NCT05340634 Completed - Clinical trials for Polycystic Ovary Syndrome

Evaluation of Metionac for the Modulation of Metabolic and Endocrine Parameters in Patients With PCOS.

Start date: April 20, 2020
Phase: Phase 4
Study type: Interventional

Evaluate the efficacy of the combination of antioxidants ALA, NAC, Vit. B6 and SAMe as a dietary supplement, in the improvement of metabolic and endocrine parameters and clinical manifestations of PCOS.

NCT ID: NCT05326087 Not yet recruiting - Clinical trials for Polycystic Ovarian Syndrome

Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-A

Start date: December 1, 2024
Phase: Phase 3
Study type: Interventional

This randomized trial aims to compare the euploid rate of blastocysts between PPOS (progestin-primed ovarian stimulation) and GnRH (gonadotrophin releasing hormone) antagonist protocols in patients with PCOS (polycystic ovary syndrome) undergoing PGT-A (preimplantation genetic testing for aneuploidy). Infertile women with PCOS will be recruited for study after explanation and counseling if they fulfill the inclusion criteria and do not have the exclusion criteria. Eligible women will be randomised into one of the two groups: Antagonist group: Women will receive antagonist once subcutaneously daily from day 6 of ovarian stimulation till the day of the ovulation trigger. PPOS group: Women will receive oral MPA (medroxyprogesterone acetate)10mg qd from Day 3 till the day of ovulation trigger. The primary outcome is the euploidy rate of blastocysts.

NCT ID: NCT05320289 Completed - Clinical trials for Polycystic Ovary Syndrome

Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue Under ULTRAsound Visualization in Women With Infertility Due to Polycystic Ovary Syndrome

ULTRA-US
Start date: May 12, 2022
Phase: N/A
Study type: Interventional

The objective of the study is to provide preliminary evidence for the safety and effectiveness of the AblaCare System in transvaginal ablation of ovarian tissue under ultrasound visualization in women with infertility due to polycystic ovary syndrome (PCOS) who have not responded to first-line ovulation induction treatment or are contraindicated for or decline such treatment.

NCT ID: NCT05311059 Completed - Clinical trials for Polycystic Ovary Syndrome

Impact of Laparoscopic Ovarian Drilling on Ovarian Reserve in Patients With Anovulatory Polycystic Ovarian Syndrome

Start date: May 30, 2018
Phase: N/A
Study type: Interventional

Pneumoperitoneum is done by insertion of the verress needle at the inferior edge of the umbilicus putting into consideration the following tests: 1. Needle test: Verress needle patency check. 2. Hissing phenomenon: Needle introduced by open valve mechanism. 3. Aspiration test: Placing a drop of water on the opening of the needle and examine its disappearance into the abdomen. 4. Volume test: Changes occurred in the intra abdominal pressure during gas insufflations. Intra abdominal pressure 12-16 mmHg usually suitable for this pelvic surgery. Introduction of the laparoscopic instruments all in its place - Laparoscopic telescope : From the inferior edge of umbilicus through trocar and sleeve which inserted by corkscrew technique then removed to allow the telescope insertion which connected to light source , camera head and color monitor. - 2nd and 3rd punctures were done allowing another two graspers to be inserted usually at a point represent outer 1/3 of the lateral abdominal wall in an imaginary line from umbilicus to iliac bone Puncturing technique : Fixation of one ovary away from intestine by grasping the ovarian ligament with the traumatic grasper which allow good exposure of the ovary and allow drilling . Drilling needle was introduced and connected by monopolar current, held against ovarian surface for 4 seconds using a power of 40 watt, 4 puncture was done in each ovary with putting into consideration that the puncture must be not superficial and it must go deep through the main substance of the ovary. Cooling of the ovary by lactated ringer's solution, finally removal of all instruments under vision after exclusion of any complication .

NCT ID: NCT05305677 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Effect of NMN (Nicotinamide Mononucleotide) on Polycystic Ovary Syndrome

NMN
Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to understand the effect of Nicotinamide mononucleotide (NMN) on patients with polycystic ovary syndrome.

NCT ID: NCT05279768 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Stem Cells and Secretomes for Infertility Therapy in Polycystic Ovary Syndrome (PCOS) Patients With Insulin Resistance.

Start date: September 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigating the effect of Umbilical Cord Mesenchymal Stem Cell (UC-MSCs) and secretomes to insulin resistance in Polycystic Ovary Syndrome (PCOS) patients. This study has 4 arms namely UC-MSCs treatment, secretomes treatment, UC-MSCs and secretomes treatment, and control.

NCT ID: NCT05272657 Not yet recruiting - Clinical trials for Polycystic Ovary Syndrome (PCOS)

Low-Carb Versus Mediterranean Diet in PCOS

Start date: March 30, 2022
Phase: N/A
Study type: Interventional

This is a randomized controlled trial of two diets (low-carbohydrate and Mediterranean diet) in the treatment of women with polycystic ovary syndrome (PCOS). The trial assesses the effects of the two diets on clinical, metabolic and hormonal parameters, inflammatory markers and gut microbiota . This study is an interventional, randomized controlled trial, open-labeled.