Standardized Emergency Care for Community Acquired Pneumonia (CAP)

Pneumonia Clinical Trial

Official title:

Reduction of Mortality in Community-Acquired Pneumonia After Implementing Standardized Care Bundles in the Emergency Department

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01963000
• Other study ID #: CAP01ED
• Status: Completed
• Phase: N/A
• First received: October 10, 2013
• Last updated: October 15, 2013
• Start date: January 2007
• Est. completion date: December 2012

Study information

• Verified date: October 2013
• Source: Klinikum Nürnberg
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Ethics Commission
• Study type: Observational

Clinical Trial Summary

Community acquired pneumonia (CAP) is associated with a high in-hospital mortality. Standardization of diagnostics and adherence to sepsis bundles in the emergency department (ED) are associated with reduced mortality in patients with sepsis. Investigators examined whether the introduction of standardized care bundles and check lists in the ED are associated with a reduced mortality rate in patients hospitalized for CAP.

This is an observational trial. The investigators retrospectively analyzed performance indicators of 2819 consecutive patients with CAP admitted to the Nuremberg Hospital, Germany, from 2008 to 2009. At the turn of the year, implementation of CAP care bundles took place including interprofessional education, checklists and institutionalized feedback. Primary endpoint was in-hospital mortality of CAP patients. After the implementation of CAP care bundles in the ED, mortality of affected patients was significantly lower in 2009 compared to 2008. This study should demonstrate that the implementation of a standardized CAP care bundle in the ED is associated with a risk reduction in affected patients. Standardization of diagnostic and therapeutic processes in the ED therefore improves the outcome of patients hospitalized for CAP.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2819
• Est. completion date: December 2012
• Est. primary completion date: December 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• all patients with community acquired pneumonia

Exclusion Criteria:

• exacerbation of chronic obstructive pulmonary disease

• malignancy

• immunosuppression

• neutropenia

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Alveolitis, Extrinsic Allergic
• Community Acquired Pneumonia
• Emergencies
• Infection
• Pneumonia

Locations

Country	Name	City	State
Germany	City Hospital Nuremberg	Nuremberg	Bavaria

Sponsors (1)

Lead Sponsor	Collaborator
Klinikum Nürnberg

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	mortality of CAP patients		up to 14days	No
Secondary	mortality up to 14days in subgroups	Mortality of patients upt to 14day is determined in subgroups (different age groups, sub-groups of CRB-risk classes); CRB-65: C mental confusion; R respiratory rate =30/min; B systolic blood pressure <90 mm Hg; 65, age =65 years	up to 14 days	No