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Clinical Trial Summary

The purpose of the study is to compare the efficacy of alternating Non Invasive Ventilation NIV and High Flow Oxygen HFO compared to High Flow Oxygen HFO alone on gas exchanges and prognosis in pneumonia-associated acute hypoxemic respiratory failure


Clinical Trial Description

Both Non Invasive Ventilation (NIV) and High Flow Oxygen through nasal cannula (HFO) are widely used in the setting of hypoxemic respiratory failure of heterogeneous etiology, with no definitive evidence for the superiority of one technique on the other. The purpose of this study is to determine whether alternating NIV and HFO brings any advantage on gas exchanges and prognosis compared to the use of HFO alone in the homogeneous setting of pneumonia-associated acute hypoxemic respiratory failure ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03758508
Study type Interventional
Source Niguarda Hospital
Contact Andrea Bellone, MD
Phone 00396444
Email andrea.bellone@ospedaleniguarda.it
Status Recruiting
Phase N/A
Start date November 1, 2017
Completion date December 1, 2025