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Clinical Trial Summary

This randomized controlled trial study aims at investigating the efficacy and safety of topical antioxidants in treatment of a cohort of non-elderly volunteers with photoaged skin.


Clinical Trial Description

•Sample size calculation: The sample size was assessed prospectively using Openepi version 3.01 to provide a 80% power to detect a 40-50% difference before and after treatment using either topical antioxidants or retinoids with a significance level of 0.05 (based on the results of a previous clinical trial). Assuming 10% dropout, 30 patients will be recruited in each treatment group. •Statistical analysis: Data will be collected and recorded on excel data sheet. Data will be tested for normality. Quantitative data will be represented as mean and standard deviation, or median and interquartile range. Qualitative data will be presented as number and percentage. The relevant statistical method will be used for comparison. P value will be considered statistically significant if it is less than 0.05 ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04835259
Study type Interventional
Source Sohag University
Contact esraa ismail
Phone 00201000509636
Email esraasalah123@yahoo.com
Status Not yet recruiting
Phase N/A
Start date April 2021
Completion date June 2022

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