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Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women

Photoaging Clinical Trial

Official title:
Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women

Clinical Trial Summary

Mangos are a rich source of nutrients such as carotenoids, vitamin C and fiber, as well as polyphenols and phenolic acids such as mangiferin, ellagic acid, and gallotannins. Mango extract has been reported to protect against photo-aging of the skin in an animal model exposed to UVB radiation, reducing the length of wrinkles and increasing collagen bundles. Beta-carotene and other carotenoids are known to provide skin protection from sunlight, but other compounds in mangos, may also be important in reducing oxidative damage in aging skin. We have recently completed a pilot study showing a clear trend in skin wrinkle reduction when postmenopausal women consumed 85g of Ataulfo mangos, four times per week for 16 weeks. To confirm and extend these results, a larger study is proposed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04869852
Study type Interventional
Source Integrative Skin Science and Research
Contact Raja Sivamani, MD, MS, AP
Phone 9165241216
Email raja.sivamani@integrativeskinresearch.com
Status Not yet recruiting
Phase N/A
Start date May 30, 2021
Completion date June 30, 2023
View Details
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