Clinical Trials Logo

Clinical Trial Summary

1. Fractional laser has become an important laser modality in management of a number of skin conditions and photoaging. Fractional photothermolysis is the fractional emission of light into microscopic treatment zones, creating small columns of injury to the skin in a pixilated fashion. Epidermal and dermal disruptions occur in these focal zones of thermal injury, stimulating dermal collagen production and elastic tissue formation. Fractional laser has been used successfully to treat photodamage and overall dyschromia in the Caucasian population. However, there is not much improvement in Asian population.

2. Photoaging refers to the skin caused by intense and chronic exposure to sunlight. The visible effects of photoaging are fine wrinkles, mottling, pigmentation and roughness of the skin. These changes are usually associated with chronologic aging. However, photoaging is not a good indicator of chronologic age. It just makes a person look older than his or her chronologic age. Skin ageing may be divided into two processes: intrinsic ageing and extrinsic ageing (or photoageing). Both are accompanied by changes in the morphological and biomechanical properties of skin.

3. Profile HaloTM dual-wavelength fusion fractional laser is the first hand tool in the world that integrates ablative and non-ablative fractional lasers. It includes a non-ablative fractional laser with a wavelength of 1470nm and an ablative fractional laser with a wavelength of 2940nm. A day after treatment, new epithelial tissue began to appear, and the necrotic epidermis formed microepidermal necrotic debris (MENDs). MENDs were surrounded by keratin 2-7 days after treatment, and collagen sequence in MTZs was changed 7 days later. The 2940 ablative fractional laser can be added with 20-100 micron lattice stripping, ensuring safety while enabling MENDs to be peeled off 2 days earlier and reducing the risk of side effects. This makes the laser safe and effective compared with the single fractional laser and reduces the downtime.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03948945
Study type Interventional
Source Xijing Hospital
Contact
Status Completed
Phase N/A
Start date October 1, 2015
Completion date October 1, 2017

See also
  Status Clinical Trial Phase
Completed NCT05271136 - A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum N/A
Completed NCT05514782 - A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum N/A
Completed NCT04911374 - An Open-Label Clinical Study to Evaluate the Efficacy of a Face Cream and Eye Cream N/A
Completed NCT04586816 - Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging N/A
Not yet recruiting NCT05004909 - Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream N/A
Completed NCT05039723 - Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational Phase 4
Completed NCT05027282 - Safety and Effectiveness of the CLEAR + BRILLIANT TOUCH(R) Diode Laser 1440-nm and 1927-nm Combination Wavelength Treatment N/A
Not yet recruiting NCT06096649 - The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin N/A
Not yet recruiting NCT06029725 - RFMN in Combination With 1927 nm Thulium Laser for Treating Photoaged Skin N/A
Completed NCT03661697 - Combination Versus Laser Treatment Only N/A
Completed NCT06148558 - A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+ N/A
Enrolling by invitation NCT06188338 - A 56-day Clinical Study on Facial Skin Rejuvenation N/A
Not yet recruiting NCT04869852 - Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women N/A
Not yet recruiting NCT02126644 - The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging Phase 2
Active, not recruiting NCT01372566 - Effect of Platelet Rich Plasma on Photoaged Skin Phase 1/Phase 2
Unknown status NCT00842907 - Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage Phase 2
Completed NCT03112863 - Comparison of the Cosmetic Effects of Bakuchiol and Retinol Early Phase 1
Recruiting NCT05386368 - RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients Phase 4
Recruiting NCT05471947 - TCA 15% Chemical Peel for Improvement in Hand Lentigines Phase 4
Completed NCT03421691 - A Single-Center Open-Label Study of 1064 nm for Nonablative Skin Rejuvenation N/A