Efficacy of Topical Antioxidants in Tretment of Photoaging

Status Not yet recruiting

Clinical Trial Summary

This randomized controlled trial study aims at investigating the efficacy and safety of topical antioxidants in treatment of a cohort of non-elderly volunteers with photoaged skin.

Clinical Trial Description

•Sample size calculation: The sample size was assessed prospectively using Openepi version 3.01 to provide a 80% power to detect a 40-50% difference before and after treatment using either topical antioxidants or retinoids with a significance level of 0.05 (based on the results of a previous clinical trial). Assuming 10% dropout, 30 patients will be recruited in each treatment group. •Statistical analysis: Data will be collected and recorded on excel data sheet. Data will be tested for normality. Quantitative data will be represented as mean and standard deviation, or median and interquartile range. Qualitative data will be presented as number and percentage. The relevant statistical method will be used for comparison. P value will be considered statistically significant if it is less than 0.05 ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04835259
Study type	Interventional
Source	Sohag University
Contact	esraa ismail
Phone	00201000509636
Email	esraasalah123@yahoo.com
Status	Not yet recruiting
Phase	N/A
Start date	April 2021
Completion date	June 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05271136` - A Clinical Study to Evaluate the Efficacy of an Anti-Aging Serum	N/A
Completed	`NCT05514782` - A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum	N/A
Completed	`NCT04911374` - An Open-Label Clinical Study to Evaluate the Efficacy of a Face Cream and Eye Cream	N/A
Completed	`NCT04586816` - Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging	N/A
Completed	`NCT05039723` - Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational	Phase 4
Not yet recruiting	`NCT05004909` - Effectivity of 1 Finger Tip Unit Compared to 2 Finger Tip Units 0.05% Tretinoin Cream	N/A
Completed	`NCT06366503` - Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation	N/A
Completed	`NCT05027282` - Safety and Effectiveness of the CLEAR + BRILLIANT TOUCH(R) Diode Laser 1440-nm and 1927-nm Combination Wavelength Treatment	N/A
Not yet recruiting	`NCT06096649` - The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin	N/A
Completed	`NCT03661697` - Combination Versus Laser Treatment Only	N/A
Completed	`NCT03948945` - Efficacy and Safety of Profile HaloTM Mixed Fractional Laser on Treating of Facial and Neck Photoaging.	N/A
Completed	`NCT06148558` - A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+	N/A
Enrolling by invitation	`NCT06188338` - A 56-day Clinical Study on Facial Skin Rejuvenation	N/A
Recruiting	`NCT06195605` - Investigating Age Dependence of Fibroblast and Extracellular Matrix Responses to Cross-linked Hyaluronic Acid Filler in Human Skin	N/A
Not yet recruiting	`NCT04869852` - Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women	N/A
Not yet recruiting	`NCT02126644` - The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging	Phase 2
Active, not recruiting	`NCT01372566` - Effect of Platelet Rich Plasma on Photoaged Skin	Phase 1/Phase 2
Unknown status	`NCT00842907` - Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage	Phase 2
Completed	`NCT03112863` - Comparison of the Cosmetic Effects of Bakuchiol and Retinol	Early Phase 1
Recruiting	`NCT05386368` - RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients	Phase 4