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Phobia, Social clinical trials

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NCT ID: NCT04111874 Completed - Clinical trials for Autism Spectrum Disorder

Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD

Start date: July 30, 2019
Phase: N/A
Study type: Interventional

This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.

NCT ID: NCT03973541 Completed - Social Anxiety Clinical Trials

CBT With VR Based Exposure for Social Anxiety Disorder

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Social Anxiety Disorder (SAD) is classified as a phobic (anxious) disorder in which the patient experiences anxiety in social interactions, during which he or she might be judged or socially evaluated by others. SAD has an estimated lifetime prevalence of 3-13%, but remains under-treated. The recommended psychological treatment for SAD is is the exposure technique imbedded in Cognitive Behavioral Therapy (CBT). Traditionally exposure has taken place either in vivo or through imaginary exposure. In vivo has shown to be most effective, but it is costly and time-consuming and situational elements, such as the reaction of others, are difficult to control. Recently, researchers and clinicians have started to use Virtual Reality (VR) to overcome such difficulties. Compared to traditional methods VR-based Exposure has several advantages mainly based on increased control. Meta-analyzes have found superior effect of CBT with VR-based Exposure compared to imaginary exposure, and similar effects when compared to in vivo exposure, with a recent study finding superior effect of VR-based Exposure compared to in vivo. The current evidence thus supports the clinical efficacy of CBT with VR-based Exposure. However, the meta-analyzes include a total of only six randomized controlled trials (RCTs) and only four of these compare CBT with VR-based Exposure to both an in vivo and a control group. The aims of the current study are to develop a complete program of CBT with VR exposure based on 360° videos for adults suffering from SAD, and to evaluate the treatment effect on SAD symptoms. The study is designed as a three arm RCT comparing 1) a group receiving CBT with VR-based Exposure, 2) a group receiving CBT with in vivo exposure and 3) a group receiving VR relaxation. CBT with VR-based Exposure, will include 360° videos with three different scenarios In Vivo Exposure Therapy consists of role-playing and guided exposure either inside or outside the therapist's office. VR Relaxation Therapy consists of a VR scenario of swimming with dolphins. Treatment will last 10 weeks and there will be a 6 months follow-up. . It is hypothesized that - CBT with VR-based Exposure will reduce symptoms of SAD - CBT with VR-based Exposure will be more effective than both CBT with in vivo exposure and VR relaxation therapy at the end of treatment - An effect on symptom reduction will sustain at the 6 months follow-up

NCT ID: NCT03925987 Completed - Clinical trials for Generalized Anxiety Disorder

Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide

Start date: June 7, 2018
Phase: N/A
Study type: Interventional

Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome. The planned study explores whether a patient's response to a physiological test involving inhalation of carbon dioxide predicts their response to exposure therapy.

NCT ID: NCT03895957 Completed - Social Phobia Clinical Trials

VR Mind and VR Mind+ Intervention

Start date: March 27, 2019
Phase: N/A
Study type: Interventional

The aim of the study is to assess the safety and efficacy of VR Mind and VR Mind + interventions.

NCT ID: NCT03885414 Completed - Social Anxiety Clinical Trials

Virtual Reality Exposure Therapy for Public Speaking Anxiety

VRETA
Start date: January 14, 2019
Phase: N/A
Study type: Interventional

Virtual Reality exposure therapy (VRET) is an efficacious treatment for anxiety disorders but has yet to be implemented in regular care settings. This is arguably due to the limitations of the past generation of VR technology, which was expensive, inaccessible, cumbersome and hard to use. With the advent of consumer VR technology, VRET is now ready for implementation in regular care. This multiple-baseline trial will examine the effectiveness of VRET for public speaking anxiety (PSA) when delivered under real-world conditions at an ordinary, non-specialized mental health clinic, by clinical psychologist with only brief VRET training. Participants will either be self-referred specifically for this treatment, or come through ordinary clinical channels. Self-rated PSA will serve as primary outcome measure and will be measured three times prior to treatment (at screening and twice after a diagnostic screening telephone interview) , four times after onset, at the end of the treatment period, and three months after treatment.

NCT ID: NCT03785223 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder Comorbidity

Start date: April 20, 2019
Phase: Phase 4
Study type: Interventional

Other psychiatric disorders, including anxiety, often co-occur with adult ADHD; with 85% of ADHD patients having at least one other psychiatric condition. The presence of a co-occurring anxiety disorder has been associated with additive clinical effects, leading to more global impairment, poorer outcome, greater resistance to treatment and increased costs of illness. Stimulants are effective first-line treatments for adult ADHD patients, however the literature has mostly examined these treatments in pure ADHD populations (i.e. without other psychiatric disorders). Thus, there is little information to guide physicians in making treatment decisions for patients with ADHD and a co-occurring condition. This trial aims to evaluate the efficacy and safety of methylphenidate hydrochloride controlled release capsules (Foquest) in treating adults aged 18-65 years with DSM-5 ADHD with and without a co-occurring anxiety disorder.The study uses a 14-week, randomized, placebo-controlled, cross-over design.

NCT ID: NCT03720795 Completed - Clinical trials for Autism Spectrum Disorder

Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This study implements a parent-led, flexible, individually-tailored cognitive-behavioral intervention for children with ASD and anxiety.

NCT ID: NCT03709615 Completed - Clinical trials for Social Anxiety Disorder

Therapeutic Processes in iCBT for SAD

Start date: December 20, 2017
Phase: N/A
Study type: Interventional

The current study examines therapeutic processes during internet-based cognitive-behavioral therapy for social anxiety disorder. Participants will be randomized to either treatment or wait-list conditions. Participants in the wait-list condition will receive active treatment following the wait-list period.

NCT ID: NCT03671577 Completed - Social Anxiety Clinical Trials

Building Closer Friendships in Social Anxiety Disorder

Start date: October 25, 2018
Phase: N/A
Study type: Interventional

This study assesses whether a 4-week computerized intervention can be used to decrease fear of intimacy, and loneliness and improve perceived social support in people with Social Anxiety Disorder.

NCT ID: NCT03647605 Completed - Social Phobia Clinical Trials

Pilot Study: VR Mind and VR Mind+ Intervention

Start date: September 13, 2018
Phase: N/A
Study type: Interventional

The aim of the pilot study is feasibility, usability and safety assessment of VR Mind intervention. In particular the subject of assessment will be: - the length of the laboratory session utilizing virtual reality exposure (feasibility), - the ergonomics and ease of use for both patients and system operators (usability), - the frequency of side effect occurrence as a result of virtual reality exposure (ie. Vertigo) (safety). The results pilot study will be used in the designing a clinical trial aimed for testing efficacy and safety of VR Mind intervention.