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Phobia, Social clinical trials

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NCT ID: NCT05193409 Completed - Clinical trials for Social Anxiety Disorder

A Phase 2 Study of BNC210 for the Acute Treatment of Social Anxiety Disorder

PREVAIL
Start date: February 2, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the effects of an acute dose of BNC210 compared to placebo on reducing anxiety provoked by a speaking challenge and measured using the Subjective Units of Distress Scale (SUDS) in patients with Social Anxiety Disorder (SAD).

NCT ID: NCT05018260 Completed - Clinical trials for Social Anxiety Disorder

Attention Bias Modification Versus Attention Control in Treatment of Social Anxiety

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the clinical efficacy of treatment using gaze contingent music reward therapy (GC-MRT) with attention control treatment based on a similar paradigm, for social anxiety disorder (SAD)

NCT ID: NCT05015166 Completed - Clinical trials for Social Anxiety Disorder

Study of an Internet-delivered Treatment Based on Experiential Dynamic Psychotherapy for Social Anxiety Disorder

STePS
Start date: August 18, 2021
Phase: N/A
Study type: Interventional

The aim of this randomized, controlled study is to examine an internet delivered, self-help program for social anxiety based on psychodynamic therapy. The study will compare three conditions: the psychodynamic program with therapist support, without therapist support and a waitlist control.

NCT ID: NCT04953338 Completed - Anxiety Disorders Clinical Trials

Mental Health Associations With Vitiligo

Start date: June 18, 2021
Phase:
Study type: Observational

This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with vitiligo compared to controls and to evaluate whether the relative risks may vary by different ethnicity.

NCT ID: NCT04922502 Completed - Clinical trials for Generalized Anxiety Disorder

Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder

Start date: July 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. A parenting intervention for youth with anxiety, called Supportive Parenting of Anxious Childhood Emotions ("SPACE"), has been recently developed to help target anxiety in children. In this intervention, therapists meet individually with parents to help them reduce anxiety behaviors in their children and support adaptive behaviors in their children. The purpose for the proposed study is to demonstrate the treatment efficacy of SPACE compared to a low-contact, therapist-supported bibliotherapy version of this intervention.

NCT ID: NCT04754802 Completed - Clinical trials for Social Anxiety Disorder

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge

Palisade-1
Start date: May 24, 2021
Phase: Phase 3
Study type: Interventional

This Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute administration of 3.2 µg of PH94B to relieve symptoms of anxiety in adult subjects with social anxiety disorder (SAD) during an induced public speaking challenge. Subject participation in the Study will last a total of 3 to 7 weeks, depending on the duration of the screening period and intervals between visits. Upon signing an informed consent, all subjects will complete Visit 1 (Screening) and enter a screening period lasting between 3 and 35 days. If subjects meet all eligibility criteria at the end of the screening period, subjects will return for Visit 2 and self-administer the nasal spray and then participate in a 5 minute public speaking challenge. During the public speaking challenge, the subject will be asked for their anxiety score, which will be recorded by a trained observer. At Visit 3, the subjects will undergo the same public speaking procedure once again as they did in Visit 2. One week after the completion of the Visit 3 public speaking challenge, the subject will come back for Visit 4 (Follow-up) that will involve a repeat of the safety and psychiatric assessments conducted at Screening.

NCT ID: NCT04729803 Completed - Clinical trials for Social Anxiety Disorder

Attention, Teleconferencing and Social Anxiety

Start date: January 18, 2021
Phase: N/A
Study type: Interventional

This study involves completing some online assessments and an intervention for social anxiety that all involve interactions with other people on a teleconferencing call.

NCT ID: NCT04179526 Completed - Clinical trials for Major Depressive Disorder

Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems

REBTonAd
Start date: January 25, 2020
Phase: N/A
Study type: Interventional

To investigate the efficacy and mechanisms of change of an Internet-delivered transdiagnostic REBT intervention for adolescents with internalizing problems.

NCT ID: NCT04111874 Completed - Clinical trials for Autism Spectrum Disorder

Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD

Start date: July 30, 2019
Phase: N/A
Study type: Interventional

This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.

NCT ID: NCT03973541 Completed - Social Anxiety Clinical Trials

CBT With VR Based Exposure for Social Anxiety Disorder

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Social Anxiety Disorder (SAD) is classified as a phobic (anxious) disorder in which the patient experiences anxiety in social interactions, during which he or she might be judged or socially evaluated by others. SAD has an estimated lifetime prevalence of 3-13%, but remains under-treated. The recommended psychological treatment for SAD is is the exposure technique imbedded in Cognitive Behavioral Therapy (CBT). Traditionally exposure has taken place either in vivo or through imaginary exposure. In vivo has shown to be most effective, but it is costly and time-consuming and situational elements, such as the reaction of others, are difficult to control. Recently, researchers and clinicians have started to use Virtual Reality (VR) to overcome such difficulties. Compared to traditional methods VR-based Exposure has several advantages mainly based on increased control. Meta-analyzes have found superior effect of CBT with VR-based Exposure compared to imaginary exposure, and similar effects when compared to in vivo exposure, with a recent study finding superior effect of VR-based Exposure compared to in vivo. The current evidence thus supports the clinical efficacy of CBT with VR-based Exposure. However, the meta-analyzes include a total of only six randomized controlled trials (RCTs) and only four of these compare CBT with VR-based Exposure to both an in vivo and a control group. The aims of the current study are to develop a complete program of CBT with VR exposure based on 360° videos for adults suffering from SAD, and to evaluate the treatment effect on SAD symptoms. The study is designed as a three arm RCT comparing 1) a group receiving CBT with VR-based Exposure, 2) a group receiving CBT with in vivo exposure and 3) a group receiving VR relaxation. CBT with VR-based Exposure, will include 360° videos with three different scenarios In Vivo Exposure Therapy consists of role-playing and guided exposure either inside or outside the therapist's office. VR Relaxation Therapy consists of a VR scenario of swimming with dolphins. Treatment will last 10 weeks and there will be a 6 months follow-up. . It is hypothesized that - CBT with VR-based Exposure will reduce symptoms of SAD - CBT with VR-based Exposure will be more effective than both CBT with in vivo exposure and VR relaxation therapy at the end of treatment - An effect on symptom reduction will sustain at the 6 months follow-up