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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT06229405
Other study ID # 2204-155-1320
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date May 10, 2022
Est. completion date December 31, 2024

Study information

Verified date February 2024
Source Seoul National University Hospital
Contact Jung Hee Kim, MD, PhD
Phone +82-10-2072-4839
Email jhee1@snu.ac.kr
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

This research aims to establish clinical evidence for optimal treatment guidelines for adrenal diseases using real-world data. The approach involves building prospective and retrospective patient registries, which will be utilized to develop and conduct research on disease-specific protocols for adrenal disorders. The study targets patients with primary aldosteronism, pheochromocytoma, adrenal cancer, adrenal incidentalomas, and mild autonomous cortisol secretion. Registries for patients with adrenal diseases will be obtained from Seoul National University Hospital and Asan Medical Center, along with securing a common data model. The ultimate goal is to conduct research to generate clinical evidence for adrenal diseases using these resources.


Description:

The ultimate goal is to develop clinical evidence for unmet needs in adrenal gland diseases using real-world data, thereby contributing to the optimization of treatment guidelines. This involves: 1. Generating real-world healthcare data through prospective and retrospective registries specific to each adrenal disease. 2. Acquiring a common data model for adrenal diseases, applicable across both domestic and international multicenter settings. 3. Creating real-world data linked with hospital medical records and public data for each adrenal disease, utilizing anonymized information merging services. 4. Developing and conducting research based on prospective and retrospective registries, a common data model, and the utilization of public-medical data for different adrenal diseases. Study Design: Prospective and retrospective patient registries. Study Population: Patients with adrenal gland disorders, including primary aldosteronism, pheochromocytoma, adrenal cancer, adrenal incidentalomas, and mild autonomous cortisol secretion Research Methods: 1. Securing prospective and retrospective registries of patients with adrenal diseases. 2. Obtaining a common data model for adrenal diseases. 3. Utilizing the secured registries and common data model for multicenter studies to generate clinical evidence for adrenal diseases. 4. Linking public and medical data with the secured registries to further research in generating clinical evidence for adrenal diseases.


Recruitment information / eligibility

Status Recruiting
Enrollment 8200
Est. completion date December 31, 2024
Est. primary completion date December 31, 2024
Accepts healthy volunteers
Gender All
Age group 19 Years and older
Eligibility Inclusion Criteria: - patients with adrenal diseases such as adrenal cortical carcinoma, Cushing's syndrome, primary aldosteronism, pheochromocytoma, adrenal incidentaloma - patients who are 19 years or older Exclusion Criteria: - patients younger than 19 years old

Study Design


Locations

Country Name City State
Korea, Republic of Seoul National University Hospital Seoul

Sponsors (7)

Lead Sponsor Collaborator
Seoul National University Hospital Asan Medical Center, Chonnam National University Hospital, Inha University Hospital, Nowon Eulji Medical Center, Samsung Medical Center, Seoul National University Bundang Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type Measure Description Time frame Safety issue
Primary Incidence rate of cardiovascular event Cardiovascular event up to 20years
Secondary Mortality rate Mortality up to 20years
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