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Pharyngitis clinical trials

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NCT ID: NCT06059248 Recruiting - General Anesthesia Clinical Trials

Effect of Different Head Positions During Endotracheal Intubation on Postoperative Sore Throat

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The goal of this [ randomized clinical trial] is to [effect of different head positions on the incidence of postoperative sore throat ] in [patients with endotracheal intubation ]. The main question it aims to answer is: the rate of postoperative sore throat will be reduced or not with the patients' head position changed during intubation.

NCT ID: NCT06027593 Recruiting - Clinical trials for Community-acquired Pneumonia

Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions

EMPOWER
Start date: October 18, 2022
Phase: N/A
Study type: Interventional

The main goal of this study is to use automated electronic reports to assess and improve guideline-concordant antibiotic use for: 1) adult inpatients with community-acquired pneumonia (CAP); 2) pediatric inpatients with CAP; 3) adult outpatients with acute pharyngitis; and 4) pediatric outpatients with acute otitis media. There are two cohorts in this study: Patients with one of the aforementioned conditions who meet inclusion criteria, and the clinicians providing clinical care to these patients.

NCT ID: NCT06011967 Completed - Clinical trials for Intubation; Difficult or Failed

Intubation With Different Angles of the Intubation Tube Using C-macr d Blade Videolaringoscope;

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

In this study we compared the intubation success, time needed for intubation, subglottic damage, postoperaitve sore throat, hoarseness and hemodynamic response to orotracheal intubation using three different intubation stylets with C-MAC R videolaryngoscope D- blade.

NCT ID: NCT06005337 Active, not recruiting - Bronchiolitis Clinical Trials

Supporting Parents to Choose Wisely

Start date: June 5, 2023
Phase: N/A
Study type: Interventional

The goal of this multi-method study including a randomized control trial and qualitative interviews is to see how useful blogshots (an image that summarizes information) are at helping parents increase their knowledge and manage their expectations for common acute childhood conditions (e.g. sore throat, ear infection) with respect to Choosing Wisely Canada recommendations. Participants will be randomly assigned to Group A or Group B in this study. Group A will receive three of six blogshots over a 4-week period (a different blogshot will be sent by email to them each week for three weeks, then in the final week they will receive the same three blogshots in one summary email to review). Group B will receive the other three of six blogshots, following the same email sequence and timing. All participants from both groups will be asked to complete one baseline questionnaire at the start of the study and a follow-up questionnaire at week 5, month 3 and month 6 about different common acute childhood conditions, the blogshots and their content. All participants also have the option to participate in an optional semi-structured interview to give their thoughts on the blogshots and their experience in the study. Researchers will compared each participant's baseline score to their follow up scores to see if there was a change in their knowledge and expectations. By developing and evaluating evidence-based Choosing Wisely Canada resources, the researchers aim to make it easier for parents to choose wisely. Empowering parents to be part of conversations with their child's healthcare provider can improve health decision-making and reduce health system costs.

NCT ID: NCT05985837 Completed - Pharyngitis Clinical Trials

Post Market Clinical Follow-Up Study - Medical Device KalobaGOLA ( PMCF )

PMCF
Start date: August 2, 2023
Phase:
Study type: Observational

The goal of this observational PMCF study is to confirm the efficacy and safety of the medical device KalobaGola (oral spray and tablets) in children, adolescents and adults with sore throat and /or pharyngitis. The main questions it aims to answer are: - Is the product effective in the treatment of sore throat / pharyingits? - Is the product safe? After buying the product, participants will be asked to fill in a questionnaire, in order to: 1. Assess the sore throat symptoms before the use of the spray or tablets. 2. Assess the resolution of sore throat / pharyngitis symptoms after the use of the spray or tablets. 3. Describe the adverse effect(s)/problem(s) observed while using the product (if any).

NCT ID: NCT05975346 Not yet recruiting - Clinical trials for Post Operative Sore Throat

Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study

Start date: August 2023
Phase:
Study type: Observational

Sore throat includes specific symptoms such as dysphagia, dysphonia, hoarseness, continuous throat pain, and pharyngeal dryness. Patients rated postoperative sore throat (POST) as the eighth most undesirable outcome in the postoperative period POST has a reported incidence of up to 62% following general anesthesia (GA). The incidence of POST is more common in GA with tracheal intubation than in GA with the supraglottic airway Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist and has been used as a gargle for reducing the incidence and severity of POST due to its anti-nociceptive and anti-inflammatory effects

NCT ID: NCT05834179 Recruiting - Clinical trials for Postoperative Sore Throat

Effect of Colding of Endotracheal Tubes on Sore Throat

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

Postoperative sore throat (POST) is a common and undesirable postoperative symptom that causes patient dissatisfaction. Cold application is a non-invasive, non-pharmacological, cost-effective and effort-effective therapy for pain management. The aim of this study was to evaluate whether colding of ETT can reduce sore throat, dysphagia and dysphonia after endotracheal intubation.

NCT ID: NCT05825872 Recruiting - Clinical trials for Postoperative Sore Throat

Ultrasound-Guided Internal Superior Laryngeal Nerve Block for Double-Lumen Bronchial Tube

Start date: April 5, 2023
Phase: Phase 4
Study type: Interventional

investigate the effectiveness and safety of ultrasound-guided bilateral internal branch of the SLN (iSLN) block for alleviating POST immediately after the operation.

NCT ID: NCT05802628 Completed - Gingivitis Clinical Trials

Salivary Drug Concentration Exploratory Study of Cetylpyridinium Chloride Buccal Tablets

Start date: April 10, 2023
Phase: Phase 4
Study type: Interventional

The study is a single-arm, open-label study to explore the salivary concentration of Cetylpyridinium Chloride Buccal Tablets after single-dose administration in Healthy Subjects

NCT ID: NCT05765162 Recruiting - Pain Clinical Trials

Safe Brain Initiative, Operationalizing Precision Anaesthesia

SBI
Start date: December 1, 2021
Phase:
Study type: Observational [Patient Registry]

Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress. Moreover, many patients develop postoperative delirium (POD) and neurocognitive dysfunctions, often resulting in long-term cognitive impairment, decreased quality of life, and increased mortality. However, physicians, nurses and their institutions do not receive structured feedback regarding these aspects of each patient's well-being. They may therefore be unable to engage in the essential cause-and-effect learning necessary to evaluate and consecutively reduce such side effects. Effective guidelines conform prevention is the proven key to shielding our patients from adverse Outcomes. The Safe Brain Initiative's high-quality routine data-for-action is a sword and accelerator for moving towards patient-centred, precision care. Thus, establishing a foundation for value-based and patient-centred healthcare development. However, a turnkey real-world solution is challenging to develop and implement and requires substantial resources. As a result, such solutions are usually beyond the scope of a single institution. The SBI platform provides high-quality, real-world data to bridge this gap. It allows monitoring and in-depth analysis of cause and effect in the day-to-day routine of individuals, departments, and institutions. The SBI's approach is continuously improved and updated. An organization called the SBI Global Society oversees the quality and precision of science through experts in the field. At SBI Hospitals and Flagship centres, Masterclasses are conducted and can be attended alongside clinical immersions. SBI Solutions manages, develops, and provides technical and service support for the Safe Brain Initiative. Its service guarantees the professional and GDPR conform management of data handling and storage as well as the user-friendly functionality of the SBI-Dashboard solutions.