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Pharyngitis clinical trials

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NCT ID: NCT06353932 Completed - Sore Throat Clinical Trials

The Effect of Monitoring Endotracheal Tube Cuff Pressure and Keeping it in a Certain Range

Start date: January 25, 2024
Phase: N/A
Study type: Interventional

The main purpose of our prospective, randomized, controlled, double-blind study is to investigate the effect of keeping endotracheal tube cuff pressures within a certain range on the incidence of postoperative sore throat, hoarseness and cough.The secondary aims of our study are to evaluate the effect of intubation duration, smoking, presence of chest disease, presence of blood on the intubation tube after extubation, presence of NG\OG, and type of surgery on the incidence of sore throat, hoarseness, and cough.The patients were randomly divided into two: a study group with continuous cuff pressure monitoring and a control group without continuous cuff pressure monitoring.The endotracheal cuff pressure of the patients in both groups was measured by a blinded researcher using a cuff manometer after intubation, before extubation, and in long cases, at the 3rd hour after intubation.Patients were evaluated for sore throat, cough, and hoarseness at the 2nd and 24th hours by another researcher blinded to the study groups.

NCT ID: NCT06271161 Completed - Postoperative Pain Clinical Trials

The Effect of Pharyngeal Cooling Applications on Postoperative Throat Pain and Nausea Vomiting

Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to to evaluate the effects of a throat pack soaked with saline at +4 ºC on postoperative throat pain (POTP) and postoperative nausea and vomiting (PONV) in dental surgical procedures performed under general anesthesia. The main questions it aims to answer are: 1. How long can we keep the pharyngeal mucosa cold using tampons and cold wash solutions? 2. Does cooling the pharyngeal mucosa reduce the incidence of postoperative sore throat and nausea and vomiting?

NCT ID: NCT06213116 Completed - Cough Clinical Trials

Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Comparing the efficacy between Lignocaine given via MADgic Atomizer and Lignocaine Pump Spray pre endotracheal intubation in adult undergoing General Anesthesia.

NCT ID: NCT06106880 Completed - Headache Clinical Trials

Alleviation of Common Cold Symptoms

Start date: May 25, 2022
Phase: Phase 1
Study type: Interventional

Upper respiratory infections (URIs) have long posed a significant burden to the US healthcare system. Well before the coronavirus disease of 2019 (COVID-19) pandemic they have been among the most common acute outpatient illnesses, causing 75-100 million physician visits each year on average, and costing the health care system billions of dollars annually. This double-blind randomized placebo-controlled study tested the efficacy of two anti-inflammatory throat sprays against placebo and against a throat spray taken in conjunction with 325mg of aspirin, a well-known systemically administered cyclooxygenase (COX) inhibitor. Participants having common cold symptoms lasting less than two days were enrolled and given treatment to administer at home. Various common cold symptoms were assessed and measured via clinically validated self-assessment scales. Participants were screened for influenza and COVID-19 before enrollment and were excluded if found positive.

NCT ID: NCT06011967 Completed - Clinical trials for Intubation; Difficult or Failed

Intubation With Different Angles of the Intubation Tube Using C-macr d Blade Videolaringoscope;

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

In this study we compared the intubation success, time needed for intubation, subglottic damage, postoperaitve sore throat, hoarseness and hemodynamic response to orotracheal intubation using three different intubation stylets with C-MAC R videolaryngoscope D- blade.

NCT ID: NCT05985837 Completed - Pharyngitis Clinical Trials

Post Market Clinical Follow-Up Study - Medical Device KalobaGOLA ( PMCF )

PMCF
Start date: August 2, 2023
Phase:
Study type: Observational

The goal of this observational PMCF study is to confirm the efficacy and safety of the medical device KalobaGola (oral spray and tablets) in children, adolescents and adults with sore throat and /or pharyngitis. The main questions it aims to answer are: - Is the product effective in the treatment of sore throat / pharyingits? - Is the product safe? After buying the product, participants will be asked to fill in a questionnaire, in order to: 1. Assess the sore throat symptoms before the use of the spray or tablets. 2. Assess the resolution of sore throat / pharyngitis symptoms after the use of the spray or tablets. 3. Describe the adverse effect(s)/problem(s) observed while using the product (if any).

NCT ID: NCT05802628 Completed - Gingivitis Clinical Trials

Salivary Drug Concentration Exploratory Study of Cetylpyridinium Chloride Buccal Tablets

Start date: April 10, 2023
Phase: Phase 4
Study type: Interventional

The study is a single-arm, open-label study to explore the salivary concentration of Cetylpyridinium Chloride Buccal Tablets after single-dose administration in Healthy Subjects

NCT ID: NCT05614414 Completed - Postoperative Pain Clinical Trials

Postoperative Sore Throat: Interest of the Videolaryngoscope

Start date: January 8, 2021
Phase: N/A
Study type: Interventional

Postoperative sore throat is a complication of orotracheal intubation. The aim of our study was to assess the impact of videolaryngoscopy on postoperative sore throat during the first 24 hours following surgery. This was a prospective, randomized study, over a period of 9 months. The investigators included 136 patients with non-difficult airway, classified ASA I to III and over 18 years old. The patients were randomized into 2 groups: the VL group including 70 patients intubated with direct laryngoscopy and the LD group including 66 patients intubated with videolaryngoscopy.

NCT ID: NCT05531617 Completed - Sore-throat Clinical Trials

A Prospective,Randomised, Open Label Study for Comparison of the Incidence and Severity of Postoperative Sore Throat (POST) Using C-MAC Video Laryngoscope and Traditional Macintosh Laryngoscope for Intubation

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to compare the incidence of postoperative sore throat after intubation with two different types of laryngoscopes.

NCT ID: NCT05522023 Completed - Surgery Clinical Trials

Effects of Aromatic Solution Applied After Surgery

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required. Complications such as sore throat, thirst and nausea and vomiting may occur as a result of trauma, local irritation and inflammation of the airway mucosa during anesthesia and tracheal intubation. These complications are in the postoperative period; It may cause delayed oral fluid intake, prolonged dehydration, oral odour, and increased risk of aspiration, hematoma and wound dehiscence due to retching and vomiting, all of which may lead to delayed discharge and increased cost. Aromatherapy, one of the non-pharmacological applications, is frequently applied in reducing postoperative complications and its effectiveness is stated. In this study, the aromatic solution applied after the surgery; It was planned to examine the effect on sore throat, thirst, nausea-vomiting. In addition, the multimodal synergistic effect of lavender oil and ginger oil used in the aromatic solution to be prepared will be utilized. As a result of this study, the effectiveness of the aromatic solution application to be applied to the patients in the postoperative period and the benefits and benefits of the patient's recovery process will be determined. Thus, effective application can be made for the entire postoperative period. It is thought that this study to be conducted will be a guide for future studies on the patient group.