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Pharyngitis clinical trials

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NCT ID: NCT01363531 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies

PDA
Start date: December 2009
Phase: Phase 4
Study type: Interventional

The general hypothesis is that delayed antibiotic treatment strategies present similar effectiveness, when compared with non-prescription of antibiotics or the prescription of antibiotics, in the non-complicated acute respiratory tract infections.

NCT ID: NCT01361802 Completed - Pain Clinical Trials

Ambroxol Spray Sore Throat Study

Start date: May 2011
Phase: Phase 2
Study type: Interventional

The development of a new Ambroxol spray formulation for the treatment of sore throat pain associated with acute pharyngitis requires an initial phase II study to be conducted in order to select the most appropriate dose for pain relief.

NCT ID: NCT01361399 Completed - Common Cold Clinical Trials

Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold

Start date: November 30, 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the analgesic efficacy of a single dose of a fixed combination of 500 mg Aspirin (Acetylsalicylic Acid) and 4 mg Lidocaine in adult patients with sore throat associated with a common cold in comparison to a single treatment with 500 mg Aspirin or 4 mg Lidocaine alone as well a Placebo (treatment without any active ingredient). The combination of Aspirin and Lidocaine in a single lozenge is expected to provide relief from sore throat pain by sequential action. A very fast inset of action will be achieved by the locally acting Lidocaine and a long duration of action will be achieved by the systemically acting Aspirin.

NCT ID: NCT01310361 Completed - Clinical trials for Streptococcal Sore Throat

Once-daily Therapy for Streptococcal Pharyngitis

Start date: January 2004
Phase: Phase 1
Study type: Interventional

In some studies once daily amoxicillin therapy might be treatment of choice for Group A β-hemolytic Streptococcus pharyngitis in comparison with three to four times daily treatment with oral penicillin V.

NCT ID: NCT01305265 Completed - Dysphagia Clinical Trials

Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique

Start date: November 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to test whether the incidence of sore throat and other tracheal co-morbidities such as dysphagia and hoarseness can be lessened by use of a cuff manometer at the beginning of surgery to inflate to the proper pressure compared to the standard technique. The investigators hypothesis is that inflation of the endotracheal balloon using a cuff manometer immediately after intubation will reduce the incidence of sore throat and other tracheal co-morbidities.

NCT ID: NCT01302769 Completed - Acute Sore Throat Clinical Trials

Ear Acupuncture for Acute Sore Throat.

Start date: October 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to compare ear acupuncture plus standard of care versus standard therapy (anti-inflammatory medications) in the reduction of pain, reduction in oral anti inflammatory medication use, hours lost from work in acute sore throat.

NCT ID: NCT01265446 Completed - Clinical trials for Sore Throat Due to a Common Cold

Efficacy and Safety of a Sore Throat Lozenge Containing Lidocaine and Cetylpyridinium Chloride in Patients With Sore Throat Due to a Common Cold.

Start date: December 2010
Phase: Phase 3
Study type: Interventional

This study will compare the efficacy and safety of a single dose of a lidocaine 8 mg + cetylpyridimium chloride (CPC) 2 mg lozenge with a single dose of a lidocaine 1 mg + CPC 2 mg lozenge in the treatment of sore throat due to a common cold.

NCT ID: NCT01156740 Completed - Pharyngitis Clinical Trials

Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings

TOPS
Start date: August 2001
Phase: N/A
Study type: Interventional

The purpose of this study was to compare the microbiological effects of two different treatments: a single dose of intramuscular benzathine penicillin G (IM BPG) vs. a 10-day daily dose of amoxicillin for the treatment of GABHS pharyngitis in children in low resource settings. This study was a prospective multi-center randomized active control treatment trial. The trial is a non-inferiority equivalence trial, to determine if amoxicillin treatment is at least as effective as the currently given IM BPG treatment.

NCT ID: NCT01118533 Completed - Sore Throat Clinical Trials

Impact of Blades Used for Scheduled Orotracheal Intubation on Postoperative Sore Throat

MPLIT
Start date: September 2010
Phase: N/A
Study type: Interventional

Orotracheal intubation following general anesthesia requires blades to be performed. The risk of patients contamination with infectious agents related to reusable metal blades leads to promote single-use blades. Some of these latter are plastic and this material may need more strength to lift the jaw and expose the larynx before orotracheal intubation. Sometimes, change of blade, from plastic to metal, during the procedure is necessary to increase the larynx exposure. This change of blade may increase the frequency of sore throat following orotracheal intubation. Consequently, the study hypothesis is an increase of both sore throat intensity and frequency with the plastic blades compared with the metal blades. The primary purpose of the present study is to compare the impact of these two types of blades, metal versus plastic, on sore throat intensity and frequency following scheduled orotracheal intubation for general anesthesia

NCT ID: NCT01062360 Completed - Common Cold Clinical Trials

Placebo and Active Controlled Study to Assess Efficacy and Tolerability of Aspirin Plus Pseudoephedrine

Start date: December 23, 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is compare efficacy and tolerability of a fixed combination, containing 500 mg Acetylsalicylic acid and 30 mg Pseudoephedrine, in comparison to its single components in patients with sore throat and nasal congestion.