Intracameral Mydriasis Versus Topical Mydriasis in Cataract Surgery

Cataract Clinical Trial

Official title: A Comparison of Intracameral Phenylephrine 2% and Tropicamide 0.2% With Topical Phenylephrine 2.5% and Tropicamide 1% for Pupillary Dilation During Cataract Surgery on Patients With and Without Pseudoexfoliation Syndrome.

Status Terminated

Clinical Trial Summary

The purpose is to determine if an intracameral solution of 0.2% tropicamide and 2% phenylephrine can dilate the pupil for cataract surgery as well as pre-operative topical 1% tropicamide and 5% phenylephrine. We will be looking at two separate groups of patients, those with and those without pseudoexfoliation syndrome.

We will be looking at how each method affects the size of the pupil at the beginning and at the end of cataract surgery. In addittion, we will look at what effect the two different methods have on blood pressure and heart rate in the pre-operative, peri-operative and post-operative periods.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Cataract
• Exfoliation Syndrome
• Mydriasis
• Phacoemulsification
• Pseudoexfoliation Syndrome

• NCT number: NCT00690222
• Study type: Interventional
• Source: Nova Scotia Health Authority
• Status: Terminated
• Phase: N/A
• Start date: March 2008
• Completion date: June 2012