Clinical Trials Logo

Clinical Trial Summary

Neonatal pulmonary hypertension is a rare but serious condition resulting from a lack of adaptation to extra-uterine life in some newborns. In the short term, the risk of death requires rapid and appropriate management of this transient pathology. In the long term, these newborns present a greater brain vulnerability, a consequence of the pathology itself with cerebral hypoxia but also invasive and aggressive therapies. Although current scientific evidence indicates a correlation with the existence of neurological developmental disorders, the understanding of the long-term neurological outcome of these babies remains poorly documented. Better knowledge of remote neuro-psychomotor development of the critical period


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04841070
Study type Interventional
Source University Hospital, Toulouse
Contact
Status Completed
Phase N/A
Start date July 25, 2021
Completion date October 29, 2021

See also
  Status Clinical Trial Phase
Completed NCT04328636 - Nebulized MgSO4 in Persistent Pulmonary Hypertension of Newborn Phase 1/Phase 2
Recruiting NCT02380040 - Plethismographic Perfusion Index in Neonates N/A
Withdrawn NCT01360671 - IV Sildenafil Persistent Pulmonary Hypertension Of The Newborn Phase 2
Terminated NCT02261883 - Remodulin as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn Phase 2
Recruiting NCT05741229 - The Effect Of Nebulizied Nitroglycerin As An Adjuvant Therapy For Persistent Pulmonary Hypertension Of Newborns N/A
Recruiting NCT00710177 - PTGS1 Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn
Completed NCT01670136 - Pharmacokinetics of Sildenafil in Premature Infants Phase 1
Completed NCT02940327 - Markers of Inflammation and Lung Recovery in ECMO Patients for PPHN
Terminated NCT01389856 - Persistent Pulmonary Hypertension of the Newborn Phase 3
Terminated NCT01069861 - Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN) Phase 2
Recruiting NCT02951130 - Milrinone in Congenital Diaphragmatic Hernia Phase 2
Enrolling by invitation NCT04938167 - Preductal Oxygen Saturation Target in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure or Pulmonary Hypertension N/A
Not yet recruiting NCT04379180 - Population Pharmacokinetics and Dosage Individualization of Oral Pulmonary Vasodilators in PPHN