Colorectal Cancer Clinical Trial
Official title:
Octreotide for Palliation of Inoperable Bowel Obstruction: A Phase II Study
RATIONALE: Palliative therapy with octreotide may help patients who have bowel obstruction
that cannot be removed by surgery to live longer and more comfortably.
PURPOSE: Phase II trial to study the effectiveness of octreotide as palliative therapy in
treating patients who have cancer-related bowel obstruction that cannot be removed by
surgery.
OBJECTIVES:
- Determine the effectiveness of octreotide in the palliation of bowel obstruction
secondary to cancer.
- Characterize the dose and tolerability of octreotide in this patient population.
OUTLINE: Patients receive octreotide subcutaneously or IV over 24 hours on days 2-5.
Patients who respond well to study may continue octreotide for palliative effects.
PROJECTED ACCRUAL: A total of 9-25 patients will be accrued for this study over 9 months.
;
Primary Purpose: Supportive Care
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