Mirror Therapy Combined With Contralaterally Controlled Functional

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

The goal of this trial is to evaluate the effects of mirror therapy combined with contralaterally controlled functional electrical stimulation on motor recovery and neuroplasticity in patients with peripheral nerve injury. The main questions it aims to answer are: Question 1: To compare corticomuscular coherence between the groups of mirror therapy combined with contralaterally controlled functional electrical stimulation, sham mirror therapy combined with contralaterally controlled functional electrical stimulation, and control group. Question 2: To compare sensorimotor recovery between the groups of mirror therapy combined with contralaterally controlled functional electrical stimulation, sham mirror therapy combined with contralaterally controlled functional electrical stimulation, and control group. Question 3: To evaluate the effects of each intervention on corticomuscular coherence and sensorimotor recovery 12 weeks post-intervention. Eligible participants will be randomized into three groups: MT and CCFES group: mirror therapy combined with contralaterally controlled functional electrical stimulation Sham MT and CCFES group: Sham mirror therapy combined with contralaterally controlled functional electrical stimulation Control group: conventional physiotherapy. Each participant will receive conventional physiotherapy for 50 minutes daily, twice a week for 12 weeks. Conventional physiotherapy includes scar management, joint range of motion exercise, strengthening, stretching, and functional training. Participants in the MT and CCFES group or Sham MT and CCFES group will receive 30 minutes daily, twice a week of the intervention for 12 weeks in addition to the conventional physiotherapy. In the MT and CCFES group, the participants will sit in front of the mirror and watch the mirror reflection of the unaffected hands. At the same time, contralaterally controlled electrical stimulation will be conducted to make the affected hands move with the unaffected hands. The participants in the Sham MT and CCFES group will sit in front of the mirror without mirror reflection, but doing the exercise with contralaterally controlled functional electrical stimulation. All participants will receive the evaluations at baseline and 12 weeks after the intervention. The evaluations include: Electroencephalography of α and β bands from the sensorimotor cortices will be recorded. Electromyography will be performed during maximum isometric pinch or lateral pinch strength measurements. Maximum isometric grip strength, tip pinch strength, lateral pinch strength, sensation tests, and upper extremity function will be measured. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06209632
Study type	Interventional
Source	National Taiwan University Hospital
Contact	Yueh-Hsia Chen, PhD
Phone	+886-3366-8133
Email	yuehhsiachen@ntu.edu.tw
Status	Recruiting
Phase	N/A
Start date	March 29, 2024
Completion date	December 31, 2027

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT02359825` - Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function	Phase 1
Not yet recruiting	`NCT02865317` - Cortical Effects of Peripheral Nerve Injury At Birth	N/A
Recruiting	`NCT01554722` - Needle Nerve Contact in Ultrasound Guided Femoral Block	N/A
Recruiting	`NCT06071988` - Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy	Phase 3
Recruiting	`NCT06071936` - Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy	Phase 3
Recruiting	`NCT05541250` - Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation in Severe Peripheral Nerve Injury (PNI)	Phase 1
Completed	`NCT01116362` - Comparing Primary With Secondary Repair of Based on Electrodiagnostic Assessment and Clinical Examination	Phase 2
Withdrawn	`NCT04270019` - Polyethylene Glycol to Improve Sensation Following Digital Nerve Laceration	Phase 1/Phase 2
Completed	`NCT01302275` - Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain	Phase 4
Terminated	`NCT01088256` - Efficacy of Etoricoxib on Peripheral Hyperalgesia	Phase 2
Completed	`NCT02228928` - Study of Capsaicin Patch for the Management of Peripheral Neuropathic Pain	Phase 1/Phase 2
Withdrawn	`NCT00950391` - Enhancement of Functional Recovery After Peripheral Nerve Injury With Tacrolimus	Phase 1/Phase 2
Completed	`NCT00953277` - Study of Nerve Reconstruction Using AVANCE in Subjects Who Undergo Robotic Assisted Prostatectomy for Treatment of Prostate Cancer	Phase 4
Not yet recruiting	`NCT06003166` - 4-AP Peripheral Nerve Crossover Trial	Phase 3
Not yet recruiting	`NCT02666456` - The Influence of Sensory Phenotype on the Risk of Developing Neuropathic Pain	N/A
Not yet recruiting	`NCT02352649` - Safety and Efficacy Study of Neovasculgen (Pl-VEGF165) Gene Therapy in Patients With Peripheral Nerve Injury	Phase 1/Phase 2
Terminated	`NCT02034461` - Micro-Electrodes Implanted in a Human Nerve	N/A
Completed	`NCT01596491` - Study of Possible Changes in QST After Application of Capsaicin on Patients With Peripheral Neuropathic Pain	N/A
Recruiting	`NCT03147313` - Extracorporal Shock Wave Treatment to Improve Nerve Regeneration	N/A

Mirror Therapy Combined With Contralaterally Controlled Functional Electrical Stimulation for Peripheral Nerve Injury

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms