Prevalence and Progression of Periodontitis in Ankylosing Spondylitis

Periodontitis Clinical Trial

Official title: The Prevalence and the Progression of Periodontitis in Ankylosing Spondylitis (AS) Patients Versus Non-AS Population

Status Completed

Clinical Trial Summary

1. Our hypotheses on the relationship between periodontitis and AS are as follows;

• The prevalence of periodontitis is higher in AS patients group than that of non-AS control group

• Anti-TNF-α therapy would favorably affect the disease course of periodontitis.

2. Based on our hypotheses, the specific objectives of the present proposal are as follows;

• The primary objective is to compare the prevalence rate of periodontitis between AS patient group and non-AS group.

• The secondary objectives will be:

• To observe the carriage rate of P. gingivalis in AS and non-AS groups

• To identify clinical parameters associated with the severity of periodontitis in AS group.

• To compare the progression of periodontitis at weeks 12 and 24 between AS and non-AS groups or between AS patients with and without anti-TNF-α treatment

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Ankylosing Spondylitis
• Periodontitis
• Spondylitis
• Spondylitis, Ankylosing

• NCT number: NCT01750528
• Study type: Observational
• Source: Seoul National University Hospital
• Status: Completed
• Phase: N/A
• Start date: September 2012
• Completion date: May 2014