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Clinical Trial Summary

1. Our hypotheses on the relationship between periodontitis and AS are as follows;

- The prevalence of periodontitis is higher in AS patients group than that of non-AS control group

- Anti-TNF-α therapy would favorably affect the disease course of periodontitis.

2. Based on our hypotheses, the specific objectives of the present proposal are as follows;

- The primary objective is to compare the prevalence rate of periodontitis between AS patient group and non-AS group.

- The secondary objectives will be:

- To observe the carriage rate of P. gingivalis in AS and non-AS groups

- To identify clinical parameters associated with the severity of periodontitis in AS group.

- To compare the progression of periodontitis at weeks 12 and 24 between AS and non-AS groups or between AS patients with and without anti-TNF-α treatment


Clinical Trial Description

n/a


Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional


Related Conditions & MeSH terms


NCT number NCT01750528
Study type Observational
Source Seoul National University Hospital
Contact
Status Completed
Phase N/A
Start date September 2012
Completion date May 2014

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