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Periodontitis clinical trials

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NCT ID: NCT03901066 Completed - Smoking Clinical Trials

Smoking Dependence and Periodontitis

Start date: September 3, 2014
Phase:
Study type: Observational [Patient Registry]

The present study was designed as a, single-center, prospective cohort study focusing on the relationship between smoking status and the severity of periodontitis

NCT ID: NCT03900013 Active, not recruiting - Clinical trials for Intrabony Periodontal Defect

Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous Defects

Start date: September 20, 2019
Phase: N/A
Study type: Interventional

Clinical and radiographic evaluation of injectable platelet rich fibrin (i-PRF) and demineralized freeze-dried bone allograft (DFDBA) compared to demineralized freeze-dried bone allograft (DFDBA) alone in management of intraosseous defects in stage III periodontitis patients.

NCT ID: NCT03882138 Completed - Clinical trials for Chronic Periodontitis

Influence of Gingival Biotype on the Outcome of Open Flap Debridement

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The influence of periodontal thickness has been documented in outcome of various periodontal interventions like non surgical periodontal therapy, mucogingival therapy, guided tissue regeneration (GTR), crown lengthening and implant dentistry. There is lack of study showing the influence of gingival biotype on outcome of surgical procedure. The present study is therefore undertaken to evaluate the influence of gingival biotype on the outcome of open flap debridement for treatment of chronic periodontitis.

NCT ID: NCT03880448 Completed - Surgery Clinical Trials

Metronidazole vs Placebo as Adjuncts to Periodontal Surgery for Patients Positive to Porphyromonas Gingivalis

Start date: September 19, 2012
Phase: N/A
Study type: Interventional

The objective of this study is to determine whether the use of a systemic antimicrobial (metronidazole) as an adjunct to periodontal surgery provides additional clinical and microbiological beneficial effects compared to periodontal surgery alone plus a placebo, in patients with non treated periodontitis (stage III and IV) positive to Porphyromonas gingivalis.

NCT ID: NCT03874390 Completed - Clinical trials for Chronic Periodontitis

Effects of Ozone Therapy on Clinical Parameters and Inflammatory Cytokines in Chronic Periodontitis Patients

Start date: October 2014
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate of ozone therapy on both clinical and biochemical effects in periodontally patients.

NCT ID: NCT03863249 Recruiting - Clinical trials for Chronic Periodontitis

Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.

Start date: February 8, 2019
Phase: Phase 4
Study type: Interventional

The aim of the study is to develop an in vitro model of growth of oral biofilms, and validate xCELLigence system for the selection of an effective antibiotic treatment for each patient.

NCT ID: NCT03862456 Active, not recruiting - Surgery Clinical Trials

Metronidazole vs Azithromycin in Periodontal Surgery for Patients Positive to Porphyromonas Gingivalis

Start date: January 2013
Phase: N/A
Study type: Interventional

The objective of this study is to determine whether, in patients with non treated periodontitis (stage III and IV) positive to Porphyromonas gingivalis, the use of systemic antimicrobials (metronidazole versus azithromycin) as an adjunctive treatment to periodontal surgery provides clinical and microbiological benefits.

NCT ID: NCT03851757 Completed - Clinical trials for Periodontitis, Adult

Cleansing Efficacy of Waist-shaped Interdental Brushes.

Waist-shaped
Start date: September 1, 2017
Phase: N/A
Study type: Interventional

The aim of the present randomized and single-blinded cross-over study was to compare the cleansing efficacy of waist-shaped interdental brushes with that of cylindric interdental brushes in interproximal sites.

NCT ID: NCT03841656 Not yet recruiting - Periodontitis Clinical Trials

Influence of Gum Disease Treatment on Long-term Dental Implant Success

Start date: March 1, 2019
Phase:
Study type: Observational

The aim of this study is to evaluate the influence of periodontal care response on long term dental implant success. Investigator's hypothesis is that patients who do not well respond to periodontal care have more chance to develop peri-implant complications at long-term. The second purpose of this study is to evaluate the influence of other local, systemic, behavioral, and implant's related risk factors

NCT ID: NCT03839719 Completed - Periodontitis Clinical Trials

OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study.

Start date: January 9, 2019
Phase: N/A
Study type: Interventional

- Periodontal disease- Inflammatory, Multifactorial, and Threshold disease. Periodontal disease is a highly prevalent dental disease, an almost 100% prevalence in developing countries. - Non-surgical periodontal includes scaling and root planing (SRP) an essential part of successful periodontal therapy. - The spread of infection through aerosol and splatter has long been considered one of the main reason for the possible transmission of infectious agents and their ill effects on The Health of patients and Dental Health care Professionals. - Aerosols are generated during Tooth preparation/Rotary instrument/ air abrasion/Air-water syringe, Ultrasonic scaler, and while doing Air polishing. - Studies have also reported an association of these aerosols with Respiratory infections, Ophthalmic and Skin infections, Tuberculosis, and Hepatitis B. current research suggests that having patients use an antimicrobial rinse before treatment may decrease microbial aerosols. - Chlorhexidine mouthwash is regarded as Gold Standard mouthwash but, have many local side effects including have many local side effects including extrinsic tooth and tongue brown staining, taste disturbance, enhanced supragingival calculus formation, less commonly, desquamation of oral mucosa, and even liver damage in rats. - In the emerging era of pharmaceuticals, herbal medicines with their naturally occurring active ingredients offer a gentle and enduring way for the restoration of health by the least harmful method. - Ocimum Sanctum (Tulsi) is known as THE QUEEN OF HERBS effective in reducing plaque accumulation, gingival inflammation, and bleeding & has no side effects as compared to Chlorhexidine. Very few studies which can be counted on fingers have been conducted worldwide in this direction, globally showing their beneficial effects.