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Periodontitis clinical trials

View clinical trials related to Periodontitis.

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NCT ID: NCT06403293 Completed - Post Operative Pain Clinical Trials

Influence of Sonic Activation of Root Sealers on Post-Operative Pain

Start date: January 16, 2023
Phase: N/A
Study type: Interventional

Aim: This clinical study aims to compare post-operative pain after single-visit root canal treatment of teeth with asymptomatic apical periodontitis using epoxy-resin based AH Plus and calcium silicate based Endosequence BC sealers with or without sonic activation. Materials and Methods: The study included 72 individuals having one first or second mandibular premolar tooth with asymptomatic apical periodontitis. They were randomly divided into 4 groups according to the root canal sealer (AH Plus or Endosequence BC) and activation protocol (sonic activation or non-activation) (n=18). Participants were ask to rate their post-operative pain intensity on a NRS scale as none, minimal, moderate, or severe after 24 h, 48 h, 72 h and 7 days following treatment. Patients were also asked to record the number of prescribed analgesic medication tablets (ibuprofen 400 mg) taken. The collected data were statistically analyzed at 0.05 significance level.

NCT ID: NCT06401798 Recruiting - Clinical trials for Periodontitis Chronic Localized Slight

Locally Delivered Whey Protein Nanoparticles Gel in Stage II Grade B Periodontitis

Start date: May 5, 2024
Phase: N/A
Study type: Interventional

Aim of the current study is to evaluate radiographic and clinical alterations following topical application of CWP gel and CWP nanoparticles gel in stage II grade B periodontitis patients.

NCT ID: NCT06400069 Not yet recruiting - Clinical trials for Chronic Periodontitis

Role of NLRP6 in Chronic Periodontitis

Start date: September 8, 2024
Phase:
Study type: Observational

The quantification of NLRP6 in blood samples will be analyzed from individuals with chronic periodontitis but without systemic disease. Demographic and periodontal parameters will be assessed and correlated with the NLRP6 quantification using RT-PCR.

NCT ID: NCT06396130 Not yet recruiting - Clinical trials for Effect of Photobiomodulation Using Diode Laser

The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical Trial

Start date: June 20, 2024
Phase: N/A
Study type: Interventional

this study aims to assess the effect of photobiomodulation using low-level diode laser therapy on postoperative pain after single-visit root canal treatment of mandibular molars with symptomatic irreversible pulpitis and apical periodontitis.

NCT ID: NCT06384638 Completed - Clinical trials for Periodontal Diseases

Coconut Oil in Treatment of Periodontitis

Start date: February 15, 2022
Phase: Phase 1
Study type: Interventional

Virgin Coconut Oil (VCO) is a vegetable oil extracted from coconut fleshcontains unsaturated fatty acids in the form of oleic acid and linoleic acid and flavonoids which function as anti-inflammatory. Periodontitis is an inflammatory disease of the periodontal tissues with a high prevalence worldwide. The main etiology of plaque periodontitis is biofilm containing colonies of pathogenic microorganisms. The aim of the study is to evaluate and compare the effect of scaling and root debridement alone versus the use of topically applied coconut oil as adjunctive to scaling and root debridement in treatment of Stage II and III Grade B periodontitis.

NCT ID: NCT06383455 Completed - Periodontitis Clinical Trials

Effects of Smoking on Clinical and Microbiological Response in Individuals With Periodontitis

Start date: September 15, 2018
Phase:
Study type: Observational

This study aimed to compare the distribution of subgingival periodontal pathogens following non-surgical periodontal therapy in smoking and non-smoking people with periodontitis. The main question it aims to answer is: - Does smoking affect the results of non-surgical periodontal treatment on subgingival flora in participants with periodontal disease? Researchers performed non-surgical periodontal therapy on 48 participants with stage III/IV periodontitis and recorded clinical measurements. They obtained subgingival plaque samples from periodontal pockets at the onset and after four weeks of treatment, determining the level of periodontopathogens using a polymerase chain reaction-based method.

NCT ID: NCT06382935 Recruiting - Periodontitis Clinical Trials

Impact of Non-surgical Periodontal Treatment of miRNome

Start date: April 20, 2024
Phase: N/A
Study type: Interventional

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid

NCT ID: NCT06382753 Recruiting - Periodontitis Clinical Trials

Impact of Periodontal Supportive Therapy in Patients With Gingivitis and Periodontitis

Start date: April 20, 2024
Phase:
Study type: Observational

The study evaluated the number of sessions of periodontal supportive treatment in patients with gingivitis in order to evaluate the risk of periodontitis development.

NCT ID: NCT06371560 Not yet recruiting - Periodontitis Clinical Trials

Antibiotics, Antibiotic Resistance, and Prescribing Practices Among Periodontists: Cross Sectional KAP Study

Start date: April 25, 2024
Phase:
Study type: Observational

Antibiotic resistance is a global health threats that require attention from all healthcare providers. In Periodontology, antibiotic is prescribed in many clinical situations. The aim of this study is to assess the followings among Periodontists (1) The knowledge, attitude, and practices (KAP) towards antibiotics and antibiotic resistance; (2) The prescribing practices of antibiotics in periodontal therapy; (3) The correlation between personal perception of antibiotics uses and the professional prescription patterns; and (4) The differences in antibiotics prescription in relation to the years of experience and the academic background.

NCT ID: NCT06366295 Recruiting - Periodontitis Clinical Trials

Comparison of Subgingival Mechanotherapy With and Without the Use of a Perioscope: Clinical Trial

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The study aims to comparatively assess clinical parameters, biochemical and microbiological parameters after treatment of periodontitis using subgingival mechanotherapy traditional and subgingival mechanotherapy using a perioscope.