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NCT05730153 Clinical Trial

Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects

Periodontitis, Adult Clinical Trial

Official title:
Clinical and Radiographic Evaluation of Advanced Platelet Rich Fibrin and Open Debridement in Management of Periodontal Suprabony Defects

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05730153
Other study ID # OMD 3-22
Secondary ID
Status Completed
Phase Phase 4
First received
Last updated
Start date November 21, 2021
Est. completion date July 26, 2022

Study information
Verified date February 2023
Source October University for Modern Sciences and Arts
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

in this clinical trial, patients with periodontal defects will be treated with advanced platelet-rich fibrin in conjunction with open debridement

Description:

two groups of patients with suprabony defects, one will be treated with advanced platelet-rich fibrin in conjunction with open debridement and the other will be treated with open debridement alone. subjects will be evaluated for evidence of bone formation after 6 months of therapy

Recruitment information / eligibility
Status Completed
Enrollment 30
Est. completion date July 26, 2022
Est. primary completion date January 27, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 60 Years
Eligibility Inclusion Criteria: - patients with periodontal suprabony defects. Exclusion Criteria: - pregnant females. - smokers. - systemic disease that contraindicate surgery

Study Design

Related Conditions & MeSH terms

Intervention

Biological:
• advanced PRF
advanced PRF+ surgery

Locations
Country Name City State
Egypt Al-Azhar University, Faculty of Dentistry Cairo

Sponsors (1)
Lead Sponsor Collaborator
October University for Modern Sciences and Arts

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary clinical evaluation Rate of probing pocket depth reduction 6 months
Secondary radiographic evaluation Rate of bone formation by digital radiography 6 months
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