Periodontal Diseases Clinical Trial
Official title:
Evaluation of Interleukin (IL)-38, IL-36-gamma, IL-17 and Matrix Metalloproteinase-9 Levels in Gingival Crevicular Fluid, Saliva and Serum for Periodontal Health, Gingivitis and Periodontitis
The aim of this study is; detection of interleukin(IL)-38, IL-36 gamma(γ) , IL-17 and matrix metalloproteinase(MMP)-9 levels in gingival crevicular fluid (GCF), saliva and serum samples of periodontally healthy, gingivitis and periodontitis patients and the possible correlation between these values and clinical parameters of periodontal diseases. Materials and methods: Samples were obtained from 90 systemically healthy non-smoker individuals with periodontitis (P, n=30), gingivitis(G, n=30) and healthy periodontium (S, n=30). Full-mouth clinical periodontal measurements including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI) and plaque index (PI) were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine IL-38, IL-36γ, IL-17 and MMP-9 levels in the biological samples.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04712630 -
Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft
|
N/A | |
Recruiting |
NCT03997552 -
NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration
|
N/A | |
Completed |
NCT04478864 -
Knowledge, Practice and State of Periodontal Health
|
||
Completed |
NCT03507868 -
YKL-40 and IL-6 Levels in Periodontal Disease
|
||
Completed |
NCT05720481 -
Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels
|
N/A | |
Recruiting |
NCT06052150 -
Oral Health In Cirrhosis of the Liver (ORACLE)
|
||
Recruiting |
NCT06025955 -
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
|
N/A | |
Recruiting |
NCT03510702 -
SCREENING OF EPIGENETIC BIOMARKERS (miRNAs) IN THE GINGIVAL SULCUS
|
||
Completed |
NCT05631600 -
Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study
|
Phase 2/Phase 3 | |
Active, not recruiting |
NCT05068778 -
Development of an AI App to Improve Compliance in Periodontal Maintenance Patients
|
||
Not yet recruiting |
NCT05178563 -
Mechanisms of Acute Inflammation Following Periodontal Treatment
|
N/A | |
Recruiting |
NCT06086821 -
Clinical Relevance of Different Time of Periodontal Re-evaluation
|
N/A | |
Recruiting |
NCT06224699 -
Toothpaste With Sodium Carbonate in Patients With Gingivitis
|
N/A | |
Not yet recruiting |
NCT05721313 -
Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study
|
N/A | |
Completed |
NCT06040944 -
Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients
|
||
Completed |
NCT06306937 -
Serum Levels of Vitamin D and IL8 in Patients With Periodontitis
|
||
Recruiting |
NCT04669717 -
Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies
|
Phase 4 | |
Completed |
NCT05576142 -
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
|
||
Completed |
NCT04017078 -
Assessment of Carotid Artery Calcifications
|
||
Not yet recruiting |
NCT03588507 -
Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects
|
N/A |