Periodontal Inflammation Clinical Trial
Official title:
The Short-Term Effects of Non-Surgical Periodontal Therapy on The Saliva Levels of S100A12, High-Sensitivity C-Reactive Protein and Fetuin-A in Patients With Gingivitis and Chronic Periodontitis
Hs-CRP, Fetuin-A and S100A12 are acute phase proteins associated with many systemic diseases
and conditions. The aim of this study was to determine the clinical parameters and salivary
Hs-CRP, Fetuin-A and S100A12 levels before and after non-surgical periodontal treatments in
the patients with periodontal diseases.
A total of 54 subjects were divided in to three groups; periodontally healthy (n: 18),
gingivitis (n: 18), chronic periodontitis (n: 18). Clinical periodontal parameters, salivary
Hs-CRP, Fetuin-A and S100A12 levels and salivary flow rates were evaluated at baseline and a
month after the treatments. Salivary Hs-CRP, Fetuin-A and S100A12 levels were assayed by
ELISA.
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