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Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion

Pericardial Effusion Clinical Trial

Official title:
Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion Following Catheter Ablation of Atrial Fibrillation

Clinical Trial Summary

The effects colchicine administration for acute pericardial effusion after radiofrequency catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.

Clinical Trial Description

RFCA was started as a rhythm control of atrial fibrillation about 10 years before and the superiority of RFCA to medical treatment has been continuously reporting, so RFCA is globally performed nowadays. Acute pericardial effusion could occur during RFCA as complication, that might be developed to cardiac tamponade needed immediate pericardiocentesis. The inflammation developed after pericardiocentesis might be associated with the recurrences of atrial fibrillation, it could be presumed by the frequent occurrence of atrial fibrillation after open-heart surgery. The inflammation can be suppressed by administration of colchicine and the effects of colchicine have been proven to decrease the development of atrial fibrillation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02260206
Study type Interventional
Source Seoul St. Mary's Hospital
Contact
Status Completed
Phase Phase 4
Start date July 2014
Completion date October 2023
View Details
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