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Periapical Periodontitis clinical trials

View clinical trials related to Periapical Periodontitis.

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NCT ID: NCT03350841 Not yet recruiting - Postoperative Pain Clinical Trials

Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis

Start date: January 2018
Phase: N/A
Study type: Interventional

randomized clinical trial which Evaluate thr Post-operative Pain Following Platelet Rich Plasma (PRP) Revascularization versus Conventional Endodontic Treatment of Non-vital Mature Mandibular Molars with Chronic Peri-apical Periodontitis

NCT ID: NCT03288467 Completed - Clinical trials for Apical Periodontitis

Effect of Sodium Hypochlorite Concentration on Success of Non-surgical Root Canal Treatment

Start date: November 6, 2016
Phase: N/A
Study type: Interventional

.There is no general agreement regarding the optimal concentration of sodium hypochlorite to be used in endodontic treatment.Therefore, this study aims to evaluate the effect of sodium hypochlorite concentration on the success of primary root canal treatment. The study population comprised of patients requiring primary root canal treatment following the diagnosis of pulpal necrosis with chronic apical periodontitis in mature mandibular first and second molars.Patients were randomly allocated in either High concentration or Low concentration group.

NCT ID: NCT03278054 Completed - Clinical trials for Apical Periodontitis

Effect of Different Instrumentation Technique on Endodontic Outcome

Start date: May 1, 2015
Phase: N/A
Study type: Interventional

Aim: To evaluate and compare the outcome of primary endodontic treatment following use of different instrumentation techniques. Materials and methods: Study subjects were recruited from the pool of patients referred for the non-surgical root canal treatment in the Department of Conservative Dentistry & Endodontics at PGIDS, Rohtak (Haryana). The study population comprised of patients requiring primary root canal treatment following the diagnosis of pulpal necrosis with chronic apical periodontitis in mature mandibular first and second molars. Subjects were allocated to one of the three study groups: manual instrumentation, ProTaper instrumentation and Hybrid instrumentation.

NCT ID: NCT03277404 Completed - Clinical trials for Apical Periodontitis

Effect of Smear Layer on Endodontic Outcome

Start date: May 7, 2015
Phase: N/A
Study type: Interventional

This study evaluated the effect of removal of smear layer on the success of primary root canal treatment.Patients requiring primary root canal treatment in mature mandibular first and second molars were allocated to either smear layer positive group and smear layer negative group.

NCT ID: NCT03243357 Recruiting - Clinical trials for Apical Periodontitis

In Vivo Assessment of Endodontics Procedures

Start date: November 22, 2017
Phase: N/A
Study type: Interventional

In view of the wide variety of mechanized endodontic instrumentation systems, the ideal would be that the choose of this system based on the anatomical characteristics of the canal and the biological precepts. In teeth with lesions, contaminated dentin should be removed. However, in many systems, the manufacturer's approach disregards the fact that in wider root canal, instruments used in the apical third small diameter (less than 0.40 mm) may not touch the walls at the final apical. Therefore, the establishment of the initial apical file (LAI), the first instrument that measures the resistance of the walls in working length, could be a criterion in the choice of which system to use, and how many files work within the root canals after LAI determination. However, there is a lack of studies that demonstrate that LAI determination affects the degree of cleaning achieved, as well as the impact that LAI-based instrumentation may have on microcracks formation, canal transportation, postoperative pain and quality of obturation.In this way, the investigators propose a study in vivo performed, in patients from 8 to 18 years of age, therefore in large root canals. The protocol recommended by the manufacturer will be compared by means of a prospective randomized clinical trial, with the addition of the XP Endo finisher and with the protocol based on the initial apical file evaluating postoperative pain, exacerbation between the sessions, the quality of the obturation and periapical radiolucency repair. Considering that currently performing endodontic treatments using mechanized instruments is taught in undergraduate courses throughout the country, studies of this nature help the execution of a endodontics more critical and effective.

NCT ID: NCT03189771 Not yet recruiting - Clinical trials for Apical Periodontitis

Effect of Occlusal Reduction on Post-operative Pain

Start date: June 27, 2017
Phase: N/A
Study type: Interventional

effect of occlusal reduction on post-operative pain is evaluated after single visit root canal treatment in upper and lower molar teeth in patients with sypmtomatic irreversible pulpitis and apical periondontis

NCT ID: NCT03171376 Completed - Clinical trials for Apical Periodontitis

Effect of Coronal Extent of Obturation on Endo-perio Lesions

Start date: October 14, 2016
Phase: N/A
Study type: Interventional

Increased incidence of apical periodontitis was reported where root filling was found coronal to the marginal bone due to communication between pulp and periodontal space. It has been suggested to place intraorifice barrier in the canal to provide coronal seal. However there exists a void in literature regarding clinical validity of the termination of obturation apical to marginal bone and placement of intraorifice barrier in resolution of periapical pathology. Therefore this randomized controlled trial intends to investigate effect of coronal level of obturation on endodontic success and marginal breakdown.

NCT ID: NCT03102879 Completed - Clinical trials for Periapical Periodontitis

Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.

RanoKure
Start date: September 23, 2016
Phase: N/A
Study type: Interventional

To compare the dental survival in a period of one year of mature permanent teeth with apical lesion following the administration of encapsulated Mesenchymal Stem Cells under a regenerative endodontic procedure and a conventional root canal treatment.

NCT ID: NCT03033472 Not yet recruiting - Clinical trials for Symptomatic Periapical Periodontitis

Effect of Preoperative Clindamycin on Postoperative Endodontic Pain

Start date: n/a
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this prospective, randomized, placebo controlled study is to evaluate the effect of clindamycin on post-operative pain and swelling in adult patient with symptomatic apical periodontitis.

NCT ID: NCT03033147 Completed - Clinical trials for Symptomatic Periapical Periodontitis

Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain

Start date: October 18, 2019
Phase: N/A
Study type: Interventional

The aim of this prospective, randomized, placebo controlled study is to evaluate the effect of a single preoperative dose of amoxicillin/clavulanic acid combination on post-operative pain and swelling in adult patient with symptomatic apical periodontitis.