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Periapical; Infection clinical trials

View clinical trials related to Periapical; Infection.

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NCT ID: NCT06307678 Completed - Clinical trials for Periapical; Infection

Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators

Start date: July 7, 2023
Phase: N/A
Study type: Interventional

Calcium hydroxide is generally preferred in endodontics as an intracanal medicament because of its antimicrobial and biological effects. However, the antimicrobial effect of calcium hydroxide is limited. The aim of this study was to investigate the effects of calcium silicate-based root canal medicament on the release of RANKL/OPG, TNF-α, PGE-2 and TGF-β1 in root canal treated teeth with periapical lesions.

NCT ID: NCT06158451 Not yet recruiting - Pain, Postoperative Clinical Trials

Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in LSTR

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate and compare the clinical effectiveness of zinc oxide-propolis mixture with triple antibiotic paste in LSTR as root canal filling material in necrotic primary molars.

NCT ID: NCT06035185 Not yet recruiting - Endodontic Disease Clinical Trials

Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical Lesion

Start date: December 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to define the role of apical shaping and irrigation activation on root canal cleanliness. The main questions it aims to answer are: - does the effectiveness of irrigation activation depends on apical shaping? - can a similar success be achieved by increasing apical shaping without irrigation activation Participants will [describe the main tasks participants will be asked to do, treatments they'll be given and use bullets if it is more than 2 items].

NCT ID: NCT06031792 Recruiting - Clinical trials for Periapical; Infection

Radiographic Assessment of the Healing Pattern Associated With Periradicular Endodontic Microsurgery

Start date: September 30, 2021
Phase: N/A
Study type: Interventional

Endodontic periradicular microsurgery is a dental procedure to treat apical periodontitis in cases in which healing has not occurred after non-surgical treatment or if it is not feasible. Recent advances in techniques and materials have resulted in more predictable outcomes. Piezotome is a new and innovative device, but limited evidence is available regarding its use in endodontics. The aim of this study is to assess the healing pattern of conventional periradicular microsurgery and piezoelectric periradicular microsurgery in 2- Dimensional and 3-Dimensional imaging, and further to perform histological analysis for the presence, location, and arrangement of bacteria in the excised apical portion of the root canal system.

NCT ID: NCT05101941 Completed - Clinical trials for Immediate Dental Implant

Immediate Dental Implant Placed in the Presence of Chronic Inflammatory Periapical Lesions

Start date: December 8, 2020
Phase: N/A
Study type: Interventional

Compromised teeth with periapical pathologies are removed before dental implant placement and sockets are left to heal. Some clinicians began to immediately place dental implants in fresh extraction sockets associated with chronic inflammatory periapical lesions and these studies revealed high success rates

NCT ID: NCT04646538 Completed - Necrotic Pulp Clinical Trials

Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Start date: June 5, 2017
Phase: Early Phase 1
Study type: Interventional

3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.

NCT ID: NCT04377698 Completed - Clinical trials for Periapical; Infection

PRF and Bone Graft in Endodontic Surgeries

Start date: January 24, 2018
Phase: Phase 4
Study type: Interventional

AIM: The aim of this study was to compare and evaluate the radiographic healing in patients undergoing apical surgery, using Freeze dried mineralized bone allograft and Platelet-rich Fibrin. OBJECTIVES: To evaluate radiographic healing after periapical surgery using Freeze dried mineralized bone allograft. To evaluate radiographic healing after periapical surgery using Platelet rich Fibrin. To compare the radiographic healing after periapical surgery using Freeze dried mineralized bone allograft and Platelet rich Fibrin. Method: Patients were selected(according to the inclusion criteria) and randomly allocated to PRF and Bone Graft groups.Following apicoectomy PRF gel and FDBA graft were prepared and placed in the osseous defect followed by placement of PRF membrane for graft stabilization and flap closure. Radiographic follow up was done at 1st, 3rd, 6th and 12th months for evaluation of healing using Molven Criteria.

NCT ID: NCT03750162 Completed - Clinical trials for Root Canal Infection

Bacteria Elimination in Retreatment Cases Using Different Disinfection Techniques

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Nonsurgical root canal retreatment may become essential when the initial endodontic treatment fails because of the persistent intracanal or extracanal infections.It has been stated that the one of the main cause of posttreatment disease is the persistent or reintroduced microorganism such as enterococcus faecalis. Supplementary disinfection techniques such as irrigation agitation methods can help elimination of bacteria from root canal systems. The aim of this in vivo study was to compare the effect of passive ultrasonic irrigation, manual dynamic activation and photodynamic therapy in reducing bacterial load in endodontic retreatment cases with periradicular lesion by using polymerase chain reaction (PCR)in a single visit root canal treatment.