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Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis — PA protocol  

Perforated Appendicitis Clinical Trial

Official title:
Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis

Clinical Trial Summary

The proposed study will investigate whether antibiotic irrigation using a gentamicin/clindamycin solution during laparoscopic appendectomy is superior in preventing postoperative wound infections and IAA in perforated appendicitis compared to suction without irrigation. This will be the first prospective study to compare these two options in pediatric PA.

Clinical Trial Description

This study is for pediatric patients who are having an appendectomy and have a perforated appendix. The purpose of this study is to see whether antibiotic irrigation using gentamicin, clindamycin and suction during the surgery works better when compared to suction alone when cleaning the stomach cavity. Arm A patients will have their abdomen irrigated with the antibiotics, gentamycin and clindamycin, and then the wound will be suctioned out. Arm B patients will not have the antibiotic irrigation but will have their wound suctioned. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04039750
Study type Interventional
Source Prisma Health-Upstate
Contact
Status Active, not recruiting
Phase Phase 2
Start date July 25, 2019
Completion date December 2025
View Details
See also
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