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Clinical Trial Summary

The objective of this study is to evaluate two standard post-operative pain regimens routinely used after laparoscopic appendectomy for perforated appendicitis. The investigators hypothesize that the use of intravenous (IV) acetaminophen in addition to IV ketorolac with narcotic pain pump will decrease time to transition off patient/nurse controlled analgesia (PCA) to oral pain medications.


Clinical Trial Description

To assess pain control, patient and family perception of pain control, time to return of bowel function defined as passage of first flatus (in days), doses of anti-emetic medications, doses of narcotic pain medications, time to toleration of regular diet (in days), narcotic associated adverse effects (nausea, emesis, respiratory depression, constipation), length of stay, and overall hospital cost in admission. Post-hospitalization the investigators will assess complications including number and reasons for emergency visits and abscess formation, length of post-hospitalization analgesic use, length of post-hospitalization narcotic use, and time to return to school. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02881996
Study type Interventional
Source Children's Mercy Hospital Kansas City
Contact
Status Completed
Phase N/A
Start date June 2014
Completion date August 2016

See also
  Status Clinical Trial Phase
Completed NCT04512196 - Surgical Site Infection in Perforated Appendicitis After Peritoneal Lavage With Super-oxidised Solution N/A
Not yet recruiting NCT03267082 - Evaluation the Role of Laparoscopic Management of Perforated Appendicitis N/A
Completed NCT00528138 - Hyperbilirubinemia in Acute Appendicitis as a Predictor of Perforation N/A
Completed NCT03289351 - Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis Phase 4
Recruiting NCT00677989 - Study on Laparoscopic Operation for Perforated Appendicitis N/A
Completed NCT00677417 - Diagnostic Value of Hyperbilirubinaemia as a Predictive Factor for Appendiceal Perforation in Acute Appendicitis N/A
Terminated NCT00540189 - Initial Versus Delayed Operation for Treatment of Complicated Appendicitis In Children N/A
Terminated NCT03795194 - Antibiotic Duration in Post-appendectomy Abscess Phase 4
Completed NCT00462020 - Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis N/A
Completed NCT04472052 - Frequency of Perforated Appendicitis in Times of COVID-19
Completed NCT03159754 - Optimal Care of Complicated Appendicitis Phase 4
Active, not recruiting NCT04039750 - Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis Phase 2
Completed NCT02724410 - Role of Intravenous Versus Home Oral Antibiotics in Perforated Appendicitis N/A
Recruiting NCT04253899 - The Management of Perforated Acute Appendicitis in Adult and Pediatric Populations N/A
Completed NCT00854815 - Irrigation Versus No Irrigation for Perforated Appendicitis N/A
Completed NCT00195923 - Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis Phase 4
Withdrawn NCT00879294 - The Effect of Gum Chewing on Postoperative Ileus N/A