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Clinical Trial Summary

This is an open label, interventional, non-randomized, phase II trial of TCR alpha/beta and CD19-depeleted allogeneic HCT in pediatric patients with hematologic disease.


Clinical Trial Description

This is a single-site, open label, interventional, non-randomized, phase II trial of TCRαβ/CD19 deplete allogeneic HCT as donor source and sole GVHD prophylaxis in pediatric patients with either malignant or non-malignant hematologic disease who are eligable for allogeneic HCT, but lack a HLA-matched sibling donor. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05288595
Study type Interventional
Source University of Colorado, Denver
Contact Kayla Pacheco
Phone 17207774151
Email kayla.pacheco@childrenscolorado.org
Status Not yet recruiting
Phase Phase 2
Start date December 2024
Completion date April 2028

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