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TCR Alpha/Beta and CD19-deplete Haplo-HSCT

Hematologic Malignancy Clinical Trial

Official title:
TCR Alpha/Beta and CD19-depleted Allogeneic Hematopoietic Cell Transplant for Malignant and Non-Malignant Disease

Clinical Trial Summary

This is an open label, interventional, non-randomized, phase II trial of TCR alpha/beta and CD19-depeleted allogeneic HCT in pediatric patients with hematologic disease.

Clinical Trial Description

This is a single-site, open label, interventional, non-randomized, phase II trial of TCRαβ/CD19 deplete allogeneic HCT as donor source and sole GVHD prophylaxis in pediatric patients with either malignant or non-malignant hematologic disease who are eligable for allogeneic HCT, but lack a HLA-matched sibling donor. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05288595
Study type Interventional
Source University of Colorado, Denver
Contact Kayla Pacheco
Phone 17207774151
Email kayla.pacheco@childrenscolorado.org
Status Not yet recruiting
Phase Phase 2
Start date December 2024
Completion date April 2028
View Details
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