Patients With Spontaneous Rupture of the Fetal Membranes Clinical Trial
Official title:
Kinetics of Inflammation Markers in Maternal Plasma (Interleukins, Matrix Metalloproteinases -MMP): Study of the Correlation With the Diagnosis of Chorioamnionitis in Women Hospitalized for Spontaneous Rupture of the Fetal Membranes (SPROM) Before 34 Weeks of Amenorrhea (WA) With no Modification in the Usual Therapy.
The principal aim of this study is to help obstetricians to diagnose chorioamniotic
infection early, in cases of premature rupture of the fetal membranes before 34 WA, by
proposing earlier and more specific markers of infection than FBC and CRP. The aim is to
reduce vital and functional risk of acute chorioamnionitis for the mother, the fetus or the
newborn,.
If the kinetics profile of one or several markers correlates strongly with the diagnosis of
chorioamnionitis, it could be used in clinical practice, possibly in the context of another
clinical study.
The results of the study presented here are destined to be published in obstetrics journals.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label