Turning Pattern of Different Body Segments During Turns and Turning Performance

Parkinson's Disease Clinical Trial

Official title:

Turning Pattern of Different Body Segments During Turns and Turning Performance in Healthy Adults and People With Parkinson's Disease

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05929781
• Other study ID #: NYCU112100AE
• Status: Not yet recruiting
• Start date: September 1, 2023
• Est. completion date: December 31, 2024

Study information

• Verified date: August 2023
• Source: National Yang Ming University
• Contact: Yea-Ru Yang, Ph.D.
• Phone: 28267000
• Email: yryang[@]nycu.edu.tw
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This is a cross-sectional exploratory study. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited. Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera. The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).

Description:

The first aim of the present study is to explore the correlation between axial segment turning pattern and turning performance in people with PD and healthy adults.

The second aim is to verify the validity and reliability of 3D motion camera in turning evaluation.

A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited.

Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera.

The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).

For the data analysis, the Shapiro-Wilk test will be used to check for normal distribution. Pearson's correlation coefficient or Spearman's rank correlation coefficient will be used to examine the correlations between axial segment initiation timing and turning performance. To verify the validity and reliability, Pearson's correlation coefficient will be used for concurrent criterion validity. Intraclass correlation one-way random model will be used for test-retest reliability, showed with intraclass correlation coefficient and 95% confidence interval. A p-value of less than 0.05 is considered statistically significant.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 75
• Est. completion date: December 31, 2024
• Est. primary completion date: July 31, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• Able to walk 5 meters without assistance device

• Able to turn independently

Exclusion Criteria:

• With neurological disorders

• MMSE< 24

• Any systemic and musculoskeletal disturbances or other causes of walking inability

Related Conditions & MeSH terms

• Parkinson Disease
• Parkinson's Disease

Locations

Country	Name	City	State
Taiwan	Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Yang Ming University

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Initiation timing (sec)	Initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning	Change from baseline at one week
Primary	Turning velocity (cm/sec)		Change from baseline at one week
Primary	Turning steps		Change from baseline at one week
Primary	Turning step length (cm)		Change from baseline at one week
Primary	Turning step width (cm)		Change from baseline at one week
Primary	Stance phase (%)		Change from baseline at one week