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Study on Serum Cystatin C and PET-DAT in Patients With Parkinson's Disease

Parkinson's Disease Clinical Trial

Official title:
The Relationship Between Serum Cystatin C and PET-DAT Study in Patients With Parkinson's Disease

Clinical Trial Summary

To investigate the relationship between serum cystatin C and dopamine receptor(DAT) loss in patients with parkinson's disease(PD)

Clinical Trial Description

Number of people suffered from Parkinson disease (PD) is increasing every year. PET imaging of dopamine transport receptors（DAT） serves as the gold standard for the diagnosis and monitoring of PD development. However, due to high costs and radiation reasons, it is not suitable for long-term follow-up. Serum cystatin C can be easily obtained and cheap as an indicator. In recent years, studies have gradually found that it is related to the progression of H&Y staging of Parkinson's disease. To this extent, we want to further explore whether it can reflect the loss of DAT in the brain. Explore whether it can partially replace the role of DAT imaging for future clinical evaluation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04926909
Study type Observational [Patient Registry]
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact BaoRong Zhang, MD
Phone 13958167260
Email brzhang@zju.edu.cn
Status Recruiting
Phase
Start date July 1, 2020
Completion date August 1, 2021
View Details
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