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Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients

Parkinson's Disease Clinical Trial

Official title:
Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients With Neuropsychiatric Disorders by Multimodal Neuroimaging

Clinical Trial Summary

The objective of this protocol is to investigate the microstructural alterations and monoaminergic function in Parkinson's disease patients with impulse control disorders and cognitive impairment by multimodal MRI and 18F-DTBZ PET imaging.

Clinical Trial Description

Study duration is expected to be completed in a period of 4 year. This study will compare the microstructural integrity by multimodal MRI imaging and monoaminergic function by18F- DTBZ PET in 35 PD patients without dementia/ICD (PD group), 35 patients with mild cognitive impairment (PD-MCI), 35 PD patients with dementia (PDD group), and 35 patients with impulse control disorders (PD-ICD group). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02599753
Study type Interventional
Source Chang Gung Memorial Hospital
Contact
Status Completed
Phase Phase 2
Start date August 2015
Completion date July 31, 2018
View Details
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