Cognitive Decline in Non-demented PD

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the relationship between attention and quality of life and how rivastigmine and atomoxetine alter attention in non-demented persons with Parkinson's disease (PD).

Clinical Trial Description

Cognitive dysfunction can occur in early stage of Parkinson's disease (PD) and increases as PD progresses. Attention deficits in PD patients with dementia strongly predict the impairment of their daily living activities.

Previous studies have shown that atomoxetine improves PD executive dysfunction and rivastigmine improves attention deficits in PD patients with dementia without worsening the motor symptoms.

The aim of this study is to examine the effect of atomoxetine and rivastigmine on attention and quality of life in PD patients without disabling cognitive impairment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01340885
Study type	Interventional
Source	Oregon Health and Science University
Contact
Status	Completed
Phase	Phase 4
Start date	January 2011
Completion date	January 2013

View Details

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