Autologous Mesenchymal Stem Cell Transplant for Parkinson's Disease

Status Terminated

Clinical Trial Summary

This study is intended to look at the safety and efficacy of the use of autologous bone marrow derived stem cell transplant in patients with advanced Parkinson's disease.

Clinical Trial Description

Parkinson's disease, a neurodegenerative disorder, still at its best can only be controlled by medical or surgical treatment. For more than two decades various groups have tried using modified cell transplants for curing this disease. Earlier results with use of fetal mesencephalic cell transplant were encouraging, but this had to be discontinued due to severe side effects.

Current interest, in the use of Mesenchymal stem cells as a pluripotent cell for developing neural cells has been the background for this study. Reliance Life sciences had found encouraging results with the use of human MSCs in Rat model of PD. Based on this and other data, Jaslok Hospital and Research Centre has initiated a pilot study to investigate the efficacy of Autologous MSCs in treating advanced PD. This cells will be harvested from bone marrow, processed at RLS laboratory and transplanted by stereotactic techniques into the striatum of the patient. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00976430
Study type	Interventional
Source	Jaslok Hospital and Research Centre
Contact
Status	Terminated
Phase	N/A
Start date	July 2009
Completion date	April 30, 2012

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