Adherence of Stalevo, Entacapone and Levodopa

Parkinson's Disease Clinical Trial

Official title:

Study of Adherence of Stalevo, Entacapone and Levodopa

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00245700
• Other study ID #: R050017
• Secondary ID: Grant from Orion
• Status: Completed
• Phase: N/A
• First received: October 27, 2005
• Last updated: May 22, 2008
• Start date: April 2005
• Est. completion date: July 2006

Study information

• Verified date: May 2008
• Source: South Glasgow University Hospitals NHS Trust
• Contact: n/a
• Is FDA regulated: No
• Health authority: United Kingdom: Research Ethics Committee
• Study type: Observational

Clinical Trial Summary

To test if combining two antiparkinson drugs into a single tablet improves accuracy of medicine intake by the patient.

To test if patients with Parkinson's disease who take medicines at regular time intervals have smoother symptom control.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: July 2006
• Gender: Both
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• Patients diagnosed with Parkinson's disease aged between 18 and 85 years fulfilling UK Brain Bank criteria.

• Current levodopa therapy prescribed on a regular basis three or more times per day but requiring entacapone because of 'wearing off'

• Able to manipulate electronic monitoring bottles and complete questionnaires

Exclusion Criteria:

• Current use of compliance aid such that study participation would be detrimental to patient's adherence

• Pregnancy or breast feeding

• Excess alcohol (over 21 units per week for women and 28 units for men)

• Mini mental state examination of less than 26.

• Severe depression (Geriatric depression score over 20)

Study Design

N/A

Related Conditions & MeSH terms

• Parkinson Disease
• Parkinson's Disease

Locations

Country	Name	City	State
United Kingdom	Southern General Hospital	Glasgow	Scotland

Sponsors (1)

Lead Sponsor	Collaborator
South Glasgow University Hospitals NHS Trust

Country where clinical trial is conducted

United Kingdom,