Parkinson's Disease (PD) Clinical Trial
Fatigue is one of the most common symptoms in individuals with Parkinson's Disease (PD). Past researches indicated that more than half of the individuals with PD demonstrated fatigue symptom. The severity of fatigue was also correlated to the quality of life in individuals with PD. Finding the contributions of the central and the peripheral factors to fatigue, building reliable fatigue indexes, and developing an effective training program for individuals with PD are very important. The purpose of this project is to develop non-invasive method to monitor central and peripheral fatigue, to establish Virtual Reality(VR) anti-fatigue ergo cycling training paradigm, and to evaluate the long term training effect in individuals with PD.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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Phase 1 | |
| Completed |
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Phase 1 | |
| Completed |
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Pharmacokinetic-pharmacodynamic Interaction Between Three Different Single Doses of BIA 9-1067 and a Single-dose of Immediate-release Levodopa/Benserazide
|
Phase 1 | |
| Completed |
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|
Phase 1 | |
| Completed |
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Phase 3 | |
| Completed |
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Pharmacokinetic-pharmacodynamic Interaction Between Each of Three Different Single Doses of BIA 9-1067 and a Single-dose of Controlled-release 100/25 mg Levodopa/Carbidopa
|
Phase 1 | |
| Completed |
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Phase 3 | |
| Withdrawn |
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Efficacy of Probiotics for Parkinson Disease (PD)
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N/A | |
| Recruiting |
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An Observational Study of Subcutaneous Infusion of ABBV-951 to Assess Change in Disease Activity and Adverse Events In Adult Japanese Participants With Advanced Parkinson's Disease
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| Completed |
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A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Infusions of ABBV-951 in Subjects With Parkinson's Disease
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Phase 1 | |
| Completed |
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An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites
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Phase 1 | |
| Completed |
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Effect of Two Multiple-dose Regimens of BIA 3-202 on the Pharmacokinetics and Motor Response of Levodopa, and on the Erythrocyte Comt Activity in Parkinson's Disease Patients
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Phase 2 | |
| Active, not recruiting |
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Extension Study To Evaluate Safety And Tolerability Of 24-Hour Daily Exposure Of Continuous Subcutaneous Infusion of ABBV-951 In Adult Participants With Parkinson's Disease
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Phase 3 | |
| Completed |
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Effect of BIA 9-1067 on the Pharmacokinetics and Pharmacodynamics of Warfarin
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Phase 1 | |
| Completed |
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Open-Label Safety Study of ADS-5102 in PD Patients With LID
|
Phase 3 | |
| Completed |
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Intranasal Glutathione in Parkinson's Disease
|
Phase 1 | |
| Recruiting |
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Real-World Study of ABBV-951 Subcutaneous Infusion to Assess Change in Disease Activity in Adult Participants With Parkinson's Disease
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||
| Completed |
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Pharmacokinetic-pharmacodynamic Interaction Between Three Different Single Doses of BIA 9-1067 and a Single-dose of Controlled-release 100/25 mg Levodopa/Benserazide
|
Phase 1 | |
| Recruiting |
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Coordinated Reset Deep Brain Stimulation
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N/A | |
| Completed |
NCT02799381 -
A Study Comparing Efficacy of Levodopa-Carbidopa Intestinal Gel/Carbidopa-Levodopa Enteral Suspension and Optimized Medical Treatment on Dyskinesia in Subjects With Advanced Parkinson's Disease (DYSCOVER)
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Phase 3 |