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Study Evaluating Intepirdine (RVT-101) on Gait and Balance in Subjects With Dementia

Alzheimer's Disease Clinical Trial

Official title:
A Phase 2, Double-blind, Randomized, Placebo-controlled Crossover Study Evaluating the Effect of RVT-101 on Gait and Balance in Subjects With Alzheimer's Disease, Dementia With Lewy Bodies, or Parkinson's Disease Dementia

Clinical Trial Summary

This study seeks to evaluate the effect of intepirdine (RVT-101) on gait and balance in patients with Alzheimer's Disease, Dementia with Lewy Bodies or Parkinson's Disease Dementia.

Clinical Trial Description

To assess the effect of intepirdine (RVT-101) versus placebo on quantitative and qualitative gait and balance parameters.

Each subject will be randomized 1:1 to one of the following sequences:

Sequence 1: AB = RVT-101 35 mg during the early treatment period and Placebo during the late treatment period

Sequence 2: BA = Placebo during the early treatment period and RVT-101 35 mg during the late treatment period

Treatment A = RVT-101 35 mg once daily.

Treatment B = Placebo once daily. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02910102
Study type Interventional
Source Axovant Sciences Ltd.
Contact
Status Completed
Phase Phase 2
Start date October 2016
Completion date November 2017
View Details
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