Pathways Mediating Impaired Postural Control in Parkinson's Disease

Status Recruiting

Clinical Trial Summary

The purpose of this project is to use transcranial magnetic stimulation (TMS) to explore the state of excitability of corticocortical and corticofugal (cortex to spinal cord, cortex to brainstem to spinal cord) pathways that project to muscles that control the legs and trunk in people with Parkinson's disease. The outcome variables will be further analyzed to understand their relationship to quantitative measures of postural instability and gait dysfunction. As such, the project can be classified as basic physiologic research. The protocol is not designed to determine if measures of corticocortical or corticofugal excitability can be used as a biomarker to predict disease progression.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Parkinson Disease

Clinical Trial Details

NCT number	NCT06464029
Study type	Observational
Source	University of Minnesota
Contact	Joshua De Kam
Phone	612-626-8052
Email	jadekam@umn.edu
Status	Recruiting
Phase
Start date	June 1, 2024
Completion date	June 10, 2027

View Details

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